摘要
目的:为评价应用乙酰半胱氨酸雾化吸入在煤工尘肺并发呼吸系统感染治疗中的疗效及安全性,便于早期采取有效的治疗措施,减少其他并发症和延缓尘肺晋期。方法:我们选择住院煤工尘肺并发呼吸系统感染患者80例,随机分为对照组40例(单纯抗感染组)、观察组40例(抗感染基础上加用雾化吸入疗法组,雾化吸入液由生理盐水、乙酰半胱氨酸颗粒、地塞米松组成),观察经治疗48h后的疗效;并对观察组40例患者按不同尘肺期别进行分析。结果:观察组疗效与对照组比较,差异有非常显著性(P<0.01);观察组中Ⅰ期、Ⅱ期、Ⅲ期煤工尘肺不同期别比较,经x^2检验,差异无显著性(P>0.05)。结论:提示,在抗感染基础上应用乙酰半胱氨酸雾化吸入治疗煤工尘肺并发呼吸系统感染疗效好,安全可靠。
Objective：To evaluate the efficacy and safety plus acetyicysteine of neblized inhalation treatment for coal worker＇s pneumoconiosis complicated by pulmonary infection in order to take early and effective treatment and reduces complications and delay period of pneumoconiosis .Methods：We chose 80 cases with pneumoconiosis complicated by pulmonary infection ,who ere randomly divided into 2 groupa,40 cases of the control group （simply anti-infective group ）,40 cases of the observation group（beyond anti-infective plus nebulized inhalation ,nebulized inhalation fluid including the physiological saline,aoctylcystcine dexamethasone）,observed by 48 hours and analyzed the patients in observation group who has defferent stages of pneumoconiosis.Results：The results showed that the effect of the obaervation group compared with the control group ,the difference was significant（P〈0.01）;Among the observation group the patients with difference satge of pneumoconiosis Ⅰ,Ⅱand Ⅲ,by the χ2 test and found there was no significant difference （P〉0.05）,Conclusions ：It shows that treatment effect of the anti-infective plus acetylcysteine nebulized inhalation for coal worker＇s pneumoconiosis complicated by pulmonary infections is safe and reliable.
出处
《中国医药导刊》
2009年第11期1867-1868,共2页
Chinese Journal of Medicinal Guide
关键词
乙酰半胱氨酸雾化吸入
煤工尘肺
呼吸系统感染
治疗
Acetylcysteine nebulized inhalation
Coal worker pnenmoconiosis
Iufections
Treatment
