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BMP-7和腹膜上皮间质转化

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摘要 腹膜间皮细胞发生上皮间质转化(EMT)是导致腹膜纤维化,继而腹膜超滤衰竭,腹透患者退出腹膜透析的主要原因之一。骨形成蛋白-7(BMP-7)是内源性的拮抗EMT的物质,它可以逆转腹膜间皮细胞的间质转化,防止腹膜纤维化的发生。本文就腹膜间皮细胞EMT的机制及BMP-7腹膜保护作用的研究进展作一综述。
出处 《国际泌尿系统杂志》 2009年第6期829-832,共4页 International Journal of Urology and Nephrology
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