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钙调神经磷酸酶和丝裂素活化蛋白激酶在调节心肌肥厚中的作用 被引量：1

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摘要 钙调神经磷酸酶和丝裂素活化蛋白激酶信号系统是调节心肌肥厚发生和发展的两条重要细胞信号通道;前者在体内病理因素刺激下活性增高而导致心肌肥厚形成,后者的3个成员胞外信号调节激酶、应激活化蛋白激酶和P38丝裂素活化蛋白激酶,在调节心肌肥厚中的作用则不同。另外,两者之间并不是孤立的,而是彼此交叉、互相协调、共同调节心肌肥厚反应。
作者 秦娜 魏立伟 黄燮南
机构地区 贵州省合肥医学院药理学教研室 河南省洛阳正骨医院临床药学室 中国人民解放军第
出处 《心脏杂志》 CAS 2009年第5期735-736,741,共3页 Chinese Heart Journal
基金 贵州省自然科学高等教育发展基金项目资助(2005110)
关键词 心肌肥厚 钙调神经磷酸酶 丝裂素活化蛋白激酶
分类号 R542.2 [医药卫生—心血管疾病]
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参考文献13

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二级参考文献16

  • 1JunREN,CindyXFANG.Small guanine nucleotide-binding protein Rho and myocardial function[J].Acta Pharmacologica Sinica,2005,26(3):279-285. 被引量：6
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心脏杂志
2009年 第5期

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