摘要
9个医疗单位的693例流行性出血热(EHF)发热期病人随机分为两组,治疗组350例每日静滴强力宁60～100 ml,连用3天。其它综合治疗同对照组。结果强力宁组发热期、低血压休克期(低休期)持续时间均短(P<0.01～0.05),低休期、少尿期出现率均低(P<0.01)。尿蛋白消失、WBC、PC、BUN和SGPT复常时间明显提前(P<0.01)。并发症出现率明显减少(P<0.01)。病死率强力宁组(0.57％)亦低于对照组(1.75％)。八项免疫学指标变化两组无差异。研究表明,强力宁能缩短EHF病程,提高越期率,促进血液、肝、肾功能尽快恢复,减少并发症,亦有降低病死率作用,但其免疫调节作用不明显。
Six hundred and ninety-three cases of epidemic hemorrhagic fever (EHF ) in 9 hospitals in the febrile stage were randomly divided into 2 groups. Each of 350 cases in the therapeutic group was given 60-100ml of potenlini per day by intravenous drip for 3 days. The combined treatment in this group was just the same as that in the control group. The results show that the duration of both the febrile stage and the hypotensive shock was shorter and the occurrence rate in both the hypotensive shock stage and the oliguric stage was lower in comparison with those of the control group ( p<0.01-0.05 ). White blood cells, the count of blood platelets, BUN and ALT returned to normal earlier than expected with disappearance of uric protein ( P<0.01 ) . The occurrence rate of complications decreased markedly ( P<0.01 ) and the case fatality rate ( 0.57％ ) was lower than that of the control group ( 1.75％ ) . There was no significant difference in 8 immunological indexes between both groups. The research show that potenlini can shorten the course of EHF, raise the overstage rate, promote the recovery of the functions of the blood,the liver and kidney and reduce EHF complications ( P<0.01 ) . It can also reduce the case fatality rate. But its function in immune adjustment is not evident.
出处
《临沂医学专科学校学报》
1990年第3期179-184,共6页
Journal of Linyi Medical College
关键词
流行性出血热
强力宁
Hemorrhagic fever, epidemic, Potenlini
Immunoassay
