摘要
目的探讨脑梗死患者糖脂代谢异常的状况。方法收集常州市第二人民医院神经内科和内分泌科2007年4月至2008年4月住院的脑梗死患者771例，未确诊糖尿病的对象均进行口服葡萄糖耐量试验（OGTT）以判断糖代谢状况。结果脑梗死住院患者中确诊糖尿病的患者为41．8％，糖代谢受损者有23．4％，总的糖代谢异常患病率为65．2％。若不进行OGTT，单纯依靠空腹血糖进行诊断，将有58．5％的糖尿病患者被漏诊。同时发现脑梗死患者中存在脂代谢异常，主要表现为高TG和低HDL-C。结论脑梗死住院患者中大多数合并糖脂代谢异常，需要通过OGTT及时准确地发现合并糖代谢异常的患者，以减少脑梗死再发。
Objective To study the epidemiological characteristics of abnormal glucose and lipid metabolism in in-patients with ischemic stroke. Methods A total number of 771 in-patients with ischemic stroke, hospitalized in the Department of Neurology/Endocrinology from Changzhou No.2 Hospital from April 2007 to April 2008 were enrolled in this study. After identifying the condition of glucose metabolism, all diagnosis-undetermined patients received oral glucose tolerance test. Results Among in-patients with ischemic stroke, 41.8% of the patients were finally diagnosed as diabetes, with 23.4% classified as ＇impaired glucose tolerance＇. The prevalence of ＇abnormal glucose metabolism＇ was 65.2% in total. If diabetes in the in-patients with ischemic stroke was diagnosed only by fast plasma glucose instead of oral glucose tolerance test, 58.5% diabetic patients would have been misdiagnosed. Abnormal lipid metabolism existed in inpatients with cerebral ischemic stroke were noticed. These abnormalities of lipid metabolism were mainly consisting of increased triglyceride and decreased HDL-C cholesterol. Conclusion The majority of in-patients with ischemic stroke appeared to have had abnormal glucose and lipid metabolism. It seemed necessary to promptly and correctly diagnose these patients with abnormal glucose metabolism by oral glucose tolerance test to reduce the chances of developing the recurrence of stroke.
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
2009年第11期1194-1197,共4页
Chinese Journal of Epidemiology
关键词
脑梗死
糖脂代谢
口服葡萄糖耐量试验
Ischemic stroke
Glucose and lipid metabolism
Oral glucose tolerance test
