摘要
目的探讨初诊中晚期非小细胞肺癌(NSCLC)证候分布及证候要素组合特点。方法对2002年1月至2007年11月间在我院住院的283例中晚期NSCLC病例进行回顾性调查,收集70项中医四诊信息,对每一病例进行辨证分型并作描述性统计学分析。结果283例中晚期NSCLC中共有25种辨证分型,出现比例较大的有:气阴两虚型、气虚型、气虚血瘀型、痰湿瘀阻型;气虚、血瘀是主要证候要素,分别占65.7%、48.4%,其他由多到少依次为阴虚、痰湿、饮停胸胁、痰热、气滞、阳虚;常见两两证素组合依次为:气虚与血瘀、气虚与阴虚、痰湿与血瘀、气虚与痰湿、阴虚与血瘀。结论初诊中晚期NSCLC证候分布具有复杂性、多样性的特点;以辨证素为切入点,证素间相互组合成证的辨证思路比较符合中晚期NSCLC临床实际。
Objective To investigate the characteristics of syndrome distribution and syndrome factor combination of advanced non-small cell lung cancer （NSCLC） of preliminary diagnosis. Methods A review survey was conducted to collect 70 items of information by TCM four diagnostic methods from 283 cases of advanced NSCLC hospitalized in our hospital from Jan. 2002 to Nov. 2007. Every case was classified according to the syndrome differentiation and given descriptive statistical analysis. Results There were 25 types of syndromes in 283 cases of advanced NSCLC. The occurrence rates of types of qiyin-deficiency, qi-deficiency, qi-deficiency and blood-stasis, and phlegm-dampness obstruction were. higher. The main syndrome factors included qi-deficiency and blood-stasis counted for 65. 7% and 48.4% respectively, and other factors are yin-deficiency, phlegm-dampness, fluid-retention in the chest and hypochondrium, phlegm-heat, qi-stagnation and yang-defieiency in a descending order. The common one-one combinations of syndrome factors included qi-defieiency and blood-stasis, qi-deficiency and yin- deficiency, phlegm-damp and blood-stasis, qi-deficiency and phlegm-damp, and yin-defic blood-stasis in a descending order. Conclusion The syndrome distribution of preliminary iency and diagnosed NSCLC was complicated and multiple. The train of thought of syndrome factor combination accords with the clinical practice of advance NSCTC from the aspect of the factors of syndrome differentiation.
出处
《北京中医药大学学报》
CAS
CSCD
北大核心
2009年第10期712-715,共4页
Journal of Beijing University of Traditional Chinese Medicine
关键词
非小细胞肺癌
中医证候
证候要素
non-small cell lung cancer
TCM syndromes
syndrome factors
