摘要
目的探讨和研究超液化碘化油联合无水乙醇栓塞治疗肾癌的临床疗效。方法采用Seldinger技术对36例中、晚期肾癌行肾动脉数字减影血管造影,经肾动脉灌注化疗药物,根据瘤体大小用超液化碘油10～30ml联合无水乙醇5～15ml混合液栓塞肿瘤组织,再用明胶海绵条栓塞肿瘤供血动脉。结果36例肾癌患者完全缓解(CR)7例(其中包括5例介入栓塞治疗后手术切除患者),部分缓解(PR)10例,无变化(NC)9例,进展(PD)10例。CR+PR+NC=26例,有效率为72.2%(26/36),CR+PR=17例,近期显效率为47.2%(17/36)。结论对不能手术切除的中、晚期肾癌患者,应用超液化碘化油联合无水乙醇栓塞治疗能改善或消除症状,提高生存质量,延长带瘤生存期。
Objective To investigate the therapeutic efficacy of embolization of renal carcinoma with ultra-fluid lipiodol and absolute alcohol. Methods Renal artery angiography was performed in 36 patients with middle-stage or advanced renal carcinoma by digital substraction angiography （DSA） with Seldinger＇s technique, followed by chemotherapeutic drugs infusion. Then the tumor was embolized by ultra-fluid lipiodol combined with absolute alcohol and the tumor-feeding artery was embolized by gelatin sponge. Results Among the 36 patients, complete remission（CR） was attained in 7 cases （19.4%）, partial remission（PR） in 10 cases （27.8%）, no change（NC） in 9 cases （25.0%） and progressive deterioration（PD） in 10 cases （27.8%）. The benefit rate （CR＋PR＋NC） was 72.2%（26/36） and the overall response rate （CR＋PR） was 47.2% （17/36）. Conclusion For patients with inoperable middle-stage or advanced renal carcinoma, embolization of tumor with ultra-fluid lipiodol and absolute alcohol may help eliminate or relieve symptoms, improve life quality and prolong the survival time.
出处
《当代医学》
2009年第29期569-571,共3页
Contemporary Medicine
关键词
肾癌
超液化碘化油
无水乙醇
栓塞
介入治疗
renal carcinoma
ultra-fluid lipiodol
absolute alcohol
embolization
interventional treatment
