摘要
报告对51例初发急性心肌梗塞(AMI)进行系列测定血清乳酸脱氢酶(LDH)同功酶活力,并与血浆磷酸肌酸激酶MB同功酶(CPK-MB)对照,观察AMI后前3天LDH_1/LDH_2比值变化的结果。AMI胸痛发作6小时内受检的23例,LDH_1/LDH_2平均比值1.02;24小时达高峰,受检44例,平均比值1.76;至AMI后72小时,51例平均比值无明显下降,为1.75。胸痛发作后6～12小时,LDH_1/LDH_2比值及CPK-MB同时明显升高者占74.1%。同时简要讨论了这些变化以及血清LDH_1/LDH_2≥1作为AMI诊断指标的临床意义。
LDH_1/LDH_2 ratio was observed serially during the first 3 days after acute myocardial infarction (AMI), and compared with CK-MB in 52 patients with the first AMI. The LDH_1/LDH_2 ratio was 1.02±0.31 (n=23) within 6h from the onset of chest pain. The ratio reached peak value (1.76±0.81, n=44) at 24h and almost unchanged at 72h (1.75±0.65, n=51) after AMI. Over 6 to 12 h following AMI, 74.1% of the patients showed a parallel increase in the LDH_1/LDH_2 ratio and CK-MB. The clinical significance of these changes and a serum LDH_1/LDH_2 ratio value equal or greater than one as an index in the diagnosis of AMI was briefly discussed. The results suggested that LDH_1/LDH_2 ratio may be used as a raliable index in the diagnosis of AMI.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
1990年第1期12-14,共3页
Journal of Clinical Cardiology
