摘要
目的:探讨针刺足三里、三阴交、太溪对糖尿病周围神经病变患者氧化应激状态的调节情况。方法:将DPN患者随机分为针刺组和药物组,采用单盲的方法,进行前瞻性研究。两组患者在药物控制血糖的基础上,针刺组采用针刺治疗,药物组采用口服甲钴胺治疗,半个月后,比较两组超氧化物歧化酶和丙二醛的治疗前后变化。结果:针刺组患者超氧化物歧化酶治疗前为(67.11±3.09),治疗后为(74.39±3.15),t=-2.018,P=0.043,有统计学意义;丙二醛治疗前为(5.73±0.52),治疗后为(4.13±0.23),t=2.987,P=0.006;而药物组超氧化物歧化酶治疗前为(60.18±2.28),治疗后为(60.68±2.66),t=-0.192,P=0.0849,无统计学意义。丙二醛治疗前为(9.08±2.26),治疗后为(6.53±0.51),t=1.206,P=0.237,无统计学意义。结论:针刺足三里、三阴交、太溪治疗糖尿病周围神经病变,可通过改善糖尿病周围神经病变患者氧化应激状态的途径实现。
Objective： Explore the regulation of oxidative stress status of acupuncture Zusanli （ST36）, Sanyinjiao （SP6）, Taixi （KI3） in diabetic peripheral neuropathy patients. Methods： It is a perspective study. The DPN patients were assigned to acupuncture group and medicine group by random. The assessing person was the single blinder. All patients＇blood glucose was controlled by medicines. The DPN of those patients in acupuncture group was treated by acupuncture; those in other group were treated by Mecobalamin. The change of superoxide dismutase （SOD） and malondialdehyde （MDA） between two groups was compared after half a month. Result ： The SOD before treatment in patients of ac- upuncture group was 67.11 ± 3.09, which was 74. 39 ± 3.15 after treatment, t = - 2.018, P = 0.043, the difference had statistical significance; MDA was 5.73 ± 0.52 pre - treatment, 4.13 ± 0.23 after treatment, t = 2.987, P = 0.006. SOD in those of medicine group was 60.18 ± 2.28 ＆ 60.68 ±2.66, t = -0. 192 ,P = 0.0849, the difference had no sig- nificance; MDA was 9.08 ± 2.26 ＆ 6.53 ± 0.51, t = 1. 206, P = 0.237, no significant. Conclusion ： Acupuncture the main points can improvement the oxidative stress status of diabetic peripheral neuropathy patients. It is an important way of acupuncture treatment diabetic peripheral neuropathy.
出处
《中华中医药学刊》
CAS
2009年第11期2385-2386,共2页
Chinese Archives of Traditional Chinese Medicine
基金
辽宁省教育厅科学技术资助项目(2004F055)
