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患者健康问卷抑郁症状群量表在综合性医院中的应用研究 被引量:228

The reliability and validity of a modified patient health questionnaire for screening depressive syndrome in general hospital outpatients
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摘要 目的检验中文版患者健康问卷(patient health questionnaire,PHQ)中抑郁症状群量表(PHQ-9)在综合性医院普通门诊患者中的信度、效度和检出率。方法600例综合性医院普通门诊患者完成中文版PHQ-9和医院焦虑抑郁量表(hospital anxiety and depression scale,HADS)自评,并接受汉密顿抑郁量表(hamilton depression scale,HAMD)的评定,抽取44名患者在完成初次评定后7-14 d内接受PHQ-9重测;抽取96例患者,在完成初次评定后2周内,接受专业研究人员的定式临床精神检查(structured clinical interview for DSM-IV,SCID)。结果PHQ-9内部一致性系数为0.857,条目间的相关系数为0.236-0.718,各条目与量表总分的相关系数为0.588-0.784,先后两次测定总分的相关系数为0.947,PHQ-9总分与HADS总分及抑郁分量表分值和HAMD总分的相关系数范围0.792-0.811,PHQ-9的灵敏度为91%,特异度为97%,Kappa=0.884。检出抑郁症状群98例,占总样本量的16.3%(95%CI:13.4%-19.3%)。结论中文版本PHQ-9在综合性医院普通门诊患者应用中具有良好的信度和效度。 Objective To evaluate the reliability and validity of a modified patient health questionnaire module named PHQ-9 with emphasis on screening of depressive syndrome in general hospital outpatients.Methods Six hundred general hospital outpatients were evaluated by using the PHQ-9. The internal reliability, test-retest reliability and validity were examined. Results Cronbach' s coefficient of PHQ-9 was 0. 857, the test-retest reliability 0. 947, and the range of correlation coefficient of the nine items with the total score of the scale 0. 588 - 0. 784. The sensitivity of PHQ-9 was 91%, the specificity 97%, and Kappa value 0. 884. PHQ -9 general The detection rate was 16.3%, (95% CI:13.4% -19.3% ). Conclusion The Chinese version of has been shown to have good reliability and validity for the screening of depressive syndrome in hospital outpatients
出处 《同济大学学报(医学版)》 CAS 2009年第5期136-140,共5页 Journal of Tongji University(Medical Science)
基金 国家863计划资助项目(2007AA02Z420) 上海市科委重点科技攻关项目(074119520) 上海市医院新兴技术项目(SHDC12006105)
关键词 患者健康问卷 抑郁症状群量表 信度 效度 检出率 patient health questionnaire PHQ-9 reliability validity detection rate
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