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胰岛素受体功能与脂联素

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摘要 脂联素作为一种脂肪组织特异性分泌的细胞因子在能量、糖脂代谢、抗动脉粥样硬化以及炎症反应等方面均发挥重要作用,其中脂联素调节胰岛素敏感性、参与胰岛素抵抗的相关作用尤其受到学者们的关注。既往的研究发现血中低脂联素水平是胰岛素抵抗的分子标志,并可以预测2型糖尿病的发生;给动物模型注射脂联素或进行体内脂联素的过表达均可增加胰岛素的敏感性、改善葡萄糖的代谢。
出处 《中华医学杂志》 CAS CSCD 北大核心 2009年第38期2729-2731,共3页 National Medical Journal of China
基金 上海市医学领军人才培养计划(LJ06010) 上海交通大学医学院博士创新基金(BXJ0827)
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