摘要
目的：探讨环磷酰胺冲击治疗狼疮性肾炎的临床价值。方法：对６４例活动性狼疮性肾炎应用环磷酰胺冲击治疗，观察疗效及副作用。结果：缓解率９０．６３％，活动控制平均所需时间３７．２±１８．５ｄ，副作用比常规环磷酰胺隔日疗法少（Ｐ＜０．０５～Ｐ＜０．０１）。结论：对狼疮性肾炎，宜首选环磷酰胺冲击治疗。
Objective:To inveastigate the effect and clinical significance of cyclophosphamide(CTX) pulse therapy in treatment of lupus nephritis.Methods:CTX pulse therapy was used in 64 cases of lupus nephritis to observe the effects and the side effects.Results:Remission rate was 90.63%.The average time for the activity of lupus nephritis to be under control in 37.2±18.5 days.The side effects are less than those caused by conventional treatment.The differences are significant as compared with the control group( P <0.05～ P < 0.01 ).Conclusions:CTX pulse therapy should be the first choice in treating lupus nephritis.
出处
《蚌埠医学院学报》
CAS
1998年第6期386-387,共2页
Journal of Bengbu Medical College
