摘要
胰岛素样生长因子１（ＩＧＦ１）是一种多功能细胞调控因子．它的结构特征为其促生长和物质代谢功能提供依据．集中介绍了ＩＧＦ１的三维结构、ＩＧＦ１与相关受体和结合蛋白的结合区以及二硫键在蛋白质折叠中的重要作用．
Insulinlike growth factor 1 is a multifunctional cell regulating factor. It has been demonstrated that structural characteristics of IGF1 provide clues for its growth promoting and anabolic effect. It is concentrated on the three dimensional structure of human IGF1, and the combining regions between IGF1 and relative receptors and binding proteins. It also shows the important role of disulfide bonds in the protein folding.
出处
《生物化学与生物物理进展》
SCIE
CAS
CSCD
北大核心
1998年第4期311-315,共5页
Progress In Biochemistry and Biophysics
关键词
结构
功能
受体
结合蛋白
IGF1
insulinlike growth factor 1, structure,function,receptor,binding proteins
