摘要
目的 探讨54岁以上患者的卒中后认知功能损害及其对患者生活质量的影响。方法运用中文版简易智能量表（MMSE）、神经功能缺损量表（NFDS）和诺丁汉健康问卷（NHP）对318例卒中患者进行现状调查。结果①318例卒中患者中，93例有卒中后认知障碍，发生率为29．2％。②认知功能损害组93例，年龄为54～86岁，平均（66±3）岁。〈60岁患者中认知功能损害有21例，占22．6％（21／93）；≥60岁患者中有72例，占77．4％（72／93），两者比较差异有统计学意义，u=2．32，P〈0．05。即≥60岁卒中后认知障碍患者的发生率高于〈60岁患者的发生率。③本组女性患者58例，发生率为50．4％（58／115），男性患者35例，发生率为17．2％（35／203），两者比较差异有统计学意义,X^2=39．085，P〈0．001，即女性发病率高于男性。④本组患者中241例有不同程度的神经功能缺损，其中93例出现认知功能损害表现，发生率为38．6％（93／241），认知功能损害患者神经功能缺损评分（12．0±2．8）；无认知功能损害患者148例的神经功能缺损评分为（8．4±2．1），两者比较差异有统计学意义，t=10．68，P〈0．001，即卒中后有认知功能障碍患者的NHP和NFDS评分高。⑤采用NI-IP问卷测定结果表明，认知功能损害组的老年人精力、情绪反应、社交隔离、躯体活动、嗜好、社会交往、与亲属关系均低于对照组（P〈0．01）。结论50岁以上卒中后认知功能障碍发生率较高，对患者的神经功能及生活质量有明显的影响。
Objective To investigate post-stroke cognitive impairment and its impact on the quality of life among patients 〉 50 years of age. Methods A survey was performed in 318 patients with stroke using the Mini-Mental Status Examination （MMSE）, Neurological functional deficit scales （NFDS） and Nottingham Health Profile （NHP）. Results①Of the 318 patients with stroke, 93 （29.2%） had poststroke cognitive impairment. ②The age of patients in the cognitive impairment group ranged from 54 to 86 years old （ mean, 65.8 - 3.4 years）. Among the patients aged 〈 60 years, 21 （22. 6% ） had cognitive impairment, among the patients aged ≥60 years, 72（77.4% ） had cognitive impairment. There was significant difference between the two groups （ n = 2.32, P 〈 0. 05 ）. （3）There were 58 （ 50.4% ） female and 35 （ 17.2% ） male patients in this group, respectively. There was significant difference between the two groups （X^2 = 39. 085 ,P 〈 0.001 ）. ④A total of 241 patients in this group had different degrees of neurological deficits. Of those, 93 had cognitive impairment, their incidence was 38.6%, and the neurological deficit score in patients with cognitive impairment was 12.0 -± 2.8 ; 148 patients did not have cognitive impairment, and their neurological deficit score was 8.4± 2.1. There was significant difference between the two groups （t = 10.68,P 〈0. 001 ） , the scores of NHP and NFDS were higher in patients with post-stroke cog-nitive impairment. ⑤The results assessed by NHP showed that the energy, emotional reaction, social isolation, physical activities, hobbies, social contact, in the cognitive impairment group were lower than those in the control group （P 〈 0.01 ）. Conclusion The incidence of post-stroke cognitive impairment is high. It had significant influence on patients＇neurological function and quality of life.
出处
《中国脑血管病杂志》
CAS
2009年第10期528-531,共4页
Chinese Journal of Cerebrovascular Diseases
关键词
卒中
认知障碍
生活质量
康复
Stroke
Cognition disorders
Qulity of life
Healing
