摘要
目的了解新疆维维吾尔（维）、汉两民族老年人轻度认知功能障碍（mild cognitive impairment，MCI）的患病情况及分布特点，为深入研究MCI的病因及其防治提供依据。方法根据美国精神病学会精神障碍诊断和统计手册第4版修订版（DSM-IV）中轻度认知功能障碍的临床诊断标准，采用随机、分层、整群抽样方式，抽取新疆南疆、东疆及乌鲁木齐地区年龄≥60岁的维族、汉族老年人，应用现场问卷调查与入户调查相结合的方法对老年人进行MCI患病情况调查。结果共调查2986人，其中维族1519人，汉族1467人；男性1435人，女性1551人。（1）按2000年全国人口普查年龄构成标化率，新疆维、汉两民族老年人群总MCI粗患病率为10．21％，标化患病率为10．58％；维族、汉族老年人MCI粗患病率分别为9．61％和10．84％，标化患病率分别为10．29％和10．86％，维、汉两民族MCI粗患病率比较，汉族略高于维族，但差异无统计学意义（X^2=1．225，P〉0．05）；（2）本次抽样调查人群中，男性、女性MCI粗患病率分别9．34％和¨．03％，标化患病率分别为9．26％和11．62％。不同性别间粗患病率比较，差异无统计学意义（X^2=2．314，P〉0．05）；（3）维族60～69岁、70～79岁和80岁及以上老年人MCI患病率分别为6．83％、13．22％和22．22％，汉族则分别为8．64％、12．50％和19．30％，两民族不同年龄段MCI粗患病率之间的差异均有统计学意义，且随着年龄的增长MCI患病率逐渐增加（X^2趋势=34．753和X^2趋势=14．081，均P〈0．05）；（4）维、汉两民族不同文化程度MCI患病率之间的差异均有统计学意义，且随受教育程度的增高MCI患病率呈现逐渐降低的趋势（X^2趋势=14．786和X^2趋势=21．059，均P〈0．05；）。结论新疆维、汉两民族老年人MCI患病率较高，不同年龄、不同文化程度老年人MCI患病率存在差异，且均随年龄的增长MCI患病率逐渐增加，随文化程度的增高MCI患病率逐渐降低。
Objective To understand the prevalence and distribution features of mild cognitive impairment（MCI）among elderly in Xinjiang Uygur and Han ethnic groups so as to provide evidence for etiological study and prevention. Methods From July 2007 to October 2008, according to the criteria of DSM IV for MCI, a randomized, stratified and cluster sampling procedure was used in the Uygur and Han elder people aged ≥60 years in south Xinjiang, east Xinjiang and Urumchi region. Results A total of 2986 people were surveyed, including 1519 Uygur people and 1467 Han people, and 1435 males and 1551 females. （1） According to the age composition of national census in 2000, the total crude prevalence rate of MCI was 10.21 %, and the total standardized prevalence rate of MCI was 10.58% in Uygur and Han elder people. In general Uygur and Han population, the crude prevalence rates of MCI were 9.61% and 10. 840%, and the standardized prevalence rates of MCI were 10.29% and 10.86%, respectively. The prevalence of MCI was higher in Han population than in Uygur population, but there was no statistical difference（X^2 =1. 225,P〉0.05）. （2） In males and females, the crude prevalence rates of MCI were 9.34% and 11.03%, and the standardized prevalence rates of MCI were 9.26% and 11.62%, respectively. There was no difference in prevalence rate between different sex populations（x^2=2.314,P2〉0.05）. （3） In elder people aged 60～69, 70N79 and ≥80 years, the MCI prevalence rates were 6.83%, 13.22% and 22. 22% in Uygur population and 8.64%, 12.50%and 19.30% in Han population, respectively, and the prevalence rate of MCI was increased with aging in the two thnic roups（xfortrend^2=34. 753, 14. 081 ,both P〈0. 05）. （4）There were statistical differences in prevalence rates of MCI among different education levels, and it was decreased with enhancement of education levels in Uygur and Han population （ xfortrend^2= 14. 785, 21. 059,both P〈0.05）. Conclusions In Xinjiang Uygur and Han ethnic elderly people, the prevalence rates of MCI are significantly different among elderly with different ages and education levels, and it is increased with aging, but is decreased with enhancement of education levels.
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
2009年第10期865-869,共5页
Chinese Journal of Geriatrics
基金
新疆维吾尔自治区自然科学基金（200821152）
关键词
人种群
认知障碍
患病率
Ethnic groups
Cognition disorders
Prevalence
