摘要
目的探讨眼局部应用1％阿托品对儿童共同性内斜视斜视角度、调节性集合和双眼视功能的影响。设计前瞻性临床研究。研究对象共同性内斜视患者35例（3—15岁）。方法1％阿托品眼用凝胶进行散瞳验光前、后分别进行斜视角度、调节性集合，调节（AC／A）、双眼视觉测定，并根据验光结果分为≤＋3D、〉＋3D并≤＋6D和〉＋6D三个不同屈光度组，对其散瞳前后的各项指标变化进行分析。主要指标斜视角度（三棱镜度）、AC／A、同时知觉、融合功能、远立体视觉、近立体视觉。结果3组患者中斜视角度≤50^Δ和≥55Δ的患者分布无显著性差异（χ2=0．52，P=0．77）；14例≤3D患者中散瞳后的斜视角度无变化者11例（78．57％），斜视角度减小者仅2例（14．29％），而11例〉3D并≤6D患者和10例〉6D患者中散瞳后斜视角度减小者均为5例（分别为45．46％和50．00％）。三组患者中，散瞳前AC／A的分布无显著性差异（χ2=4．87，P=0．30）。散瞳后各组AC／A均有减小的趋势，变化无显著性差异（χ2=1．89，P=0．75）。5例具有不同程度双眼视觉者，其斜视角度均≤20Δ。结论在儿童共同性内斜视中，低度远视患者散瞳前后斜视角度无明显变化，部分中、高度远视患者散瞳后斜视角度有减小趋势。
Objective To investigate the effect of topical use of atropine 1% on the magnitude of deviation, ratio of accommodation convergence/accommodation （AC/A） and binocular vision in children eomitant esotropia. Design Prospective clinical study. Participants Thirty-five patients （aged 3 to 15 years） with eomitant esotropia from Beijing Tongren Eye Center. Methods All patients received atropine eye-gel 1% 3 times a day for 3 days. Refraction examination was performed before and after topical use of atropine 1%. Patients were divided into three groups （≤＋3D, 〉＋3D and ≤＋6D, and 〉＋6D） based on refraction after cycloplegia. Main Outcome Measures Magnitude of deviation, ratio of AC/A, simuhaneous perception, fusion, distance stereoacuity and near stereoacuity. Results There were no significant differences among the magnitudes of deviation in three groups （χ2=0.52, P=0.77）. The ratios of patients whose deviation decreased after eyclnplegia were 14.29%, 45.46%, and 50.00% respectively in three groups. The AC/A ratio was decreased after cycloplegia in three groups but differences among three groups were not significant （χ2=1.89, P=0.75）. Only 5 patients with esotropia 〈~ 20A bad different degrees of binocular vision. Conclusion After eycloplegia with atropine, the angle of deviation in children comitant esotropia with low hypermetropia changes little, but a trend of decrease is demonstrated in some patients with moderate and high hypermetropia.
出处
《眼科》
CAS
2009年第5期304-307,共4页
Ophthalmology in China
