摘要
目的:研究CN0舌鳞癌病例中颈淋巴结隐匿性转移(PN1)、隐匿性微转移(简称微转移,PNm+)病例与确无淋巴结转移(PN0)的病例三者间预后的关系,以确定PNm+病例是否如PN1病例一样需在术后补充放射治疗。方法:①.搜集福建省肿瘤医院自1993.8～2002.11间的CNO舌鳞癌病例54例。②.对PN0病例用免疫组化染色(IHC)法结合连续切片查找PNm+病例。③.分别统计PN1、PNm+、PN0组的死亡率及生存期。④.对采集的数据用SPSS10.0软件进行统计学处理。结果:至研究结束时止,所有复发病例均已死亡,PN1组与PNm+组间的死亡率没有显著性差异;PN1组与PN0组间以及PNm+组与PN0组间存在显著性差异。PN1组与PNm+组的生存期没有显著性差异;PN1组与PN0组以及PNm+组与PN0组间生存期存在显著性差异。结论:PN1组与PNm+组病例的预后相似,均较PN0组预后差,从而证明了PNm+病例和PN1病例一样,需要在手术后进行辅助放疗。
Objective：To investigate the relationship of the prognosis of the patients suffering tongue squamous cell carcinoma （SCC） with cervical lymph node occult metastasis （PN1）, micro metastasis （PNm＋）, none metastasis （PN0）, in order to definite whether the patients with PNm＋ need postoperative radiotherapy as PN1. Method：（1） Collect 54 cases of CN0 tongue SCC treated in FuJian tumour hospital, ranged from Aug. 1993 to Nov. 2002. （2） All the paraffin block of PN0 was restudied by immunohistochemistry stain （IHC） with step section. （3） To add up the rate of death and the survival time. （4） All the data were analysesed with SPSS 10.0. Result： To the end of this study, all the patients with recurrence were dead. There is no significance in the ratio of death between the group PN~ and PNm＋, and a significance between group PN1 and PNo as between the group PN m＋1 and PN0- There is no significance in survival time between group PN1 and PNm＋, and a sig- nificance between the group PN1 and PN0 as between the group PNm＋ and PN0. Conclusion：The prognosis of the patients with PNm＋ is equivalent with the patients with PN1 . And they are poorer than the patients with PN0. The patients with PNm＋ need postoperative adjuvant radiotherapy as the patients with PN1-.
出处
《临床口腔医学杂志》
2009年第10期587-589,共3页
Journal of Clinical Stomatology
关键词
舌鳞癌
隐匿性转移
微转移
预后
免疫组织化学
squamous cell carcinoma situ in tongue
occult metastasis
micro metastasis
prognosis
immunohisto-chemistry
