摘要
目的 评价纳络酮和东莨菪碱在急性炮烟中毒治疗中的临床应用效果。方法急性炮烟中毒12例为治疗组，在常规治疗的基础上，加用纳络酮、东莨菪碱；另取前期本院急性炮烟中毒病案资料8例作为对照组，在常规治疗的基础上，使用呼吸兴奋药尼可刹米或络备林。结果两组患者均痊愈出院，治疗组在平均住院天数上明显优于对照组（t检验，P〈0．01），在促进清醒、控制抽搐、防治肺水肿的治疗上有较大优势（X^2检验，P〈0．05），在改善头痛、乏力等症状上也有较好疗效（矿检验，P〉0．05）。结论纳络酮、东莨菪碱治疗急性炮烟中毒优于尼可刹米等常规治疗方法，而且具有疗效好、不良反应少、安全可靠等特点，可以作为急性炮烟中毒抢救治疗的有效方法之一。
Objective To evaluate the effect of clinical application of scopolamine and naloxone in the treatment of acute poisoning by blasting fume. Methods 12 cases of aeute poisoning by blasting fume as the treatment group, were treated with scopolamine and naloxone on the basis of the conventional therapy, and another 8 cases data of aeute blasting fume poisoning in the hospital earlier stage as the control group, were treated with Nikethamide or Lobeline. on the basis of the conventional therapy again. Results Two groups of patients were fully recovered. The treatment group in the average number of days stay in the hospital were much better than the control group （ t test, P 〈 0. 01 ）, and in promoting to regain consciousness, curing convulsive, preventing and treating to pulmonary edema could have more advantages （X^2 test, P 〈 0. 05 ）, There were very good effects in improve symptoms such as headache, fatigue and so on（ X^2 test,P 〉0.05）. Conclusion Scopolamine and naloxone in the treatment of acute poisoning by blasting fume is superior to conventional treatment, such as nikethamide, and there are better efficacy, less side effects, more safety and reliability. It can be used as one of the effective ways to cure acute poisoning by blasting fume.
出处
《中国临床实用医学》
2009年第11期48-49,共2页
China Clinical Practical Medicine
关键词
纳络酮
东莨菪碱
炮烟中毒
治疗
Naloxone
Scopolamine
Blasting Fume Poisoning
Treatment
