摘要
目的比较足月儿与早产儿新生儿坏死性小肠结肠炎(NEC)的危险因素及临床症状。方法选择2001年4月至2008年8月我院收治的86例NEC患儿,对其临床资料进行回顾性分析。结果足月儿组围生期窒息缺氧(45%vs.12%)、晚期肠道感染(23%vs.5%)、肠道畸形(12%vs.0)致NEC发病显著高于早产儿组(P<0.05),早产儿组硬肿症(19%vs.5%)、呼吸窘迫综合征(12%vs.0)、呼吸暂停(19%vs.2%)致NEC发病显著高于足月儿组(P<0.05)。临床症状中足月儿组有便血症状者较早产儿组显著增加(32%vs.12%),早产儿组呕血(29%vs.1%)、肌张力减低(29%vs.11%)、体温不升(29%vs.9%)者较足月儿组显著增加。结论足月儿、早产儿发生NEC的危险因素各有侧重,临床症状各有特点,防治各胎龄段新生儿高危疾病及注意临床症状特点对于减少NEC的发病有所帮助。
Objective To compare the risk factors and clinical features of neonatal necrotizing enterocolitis （NEC） between full term infants and premature infants. Methods Eighty-six NEC patients from April 2001 to August 2008 were enrolled in the present study, and all the clinical data were analyzed retrospectively. Results Chi-square test showed that asphyxiation in perinatal period, late onset intestinal infection, congenital malformation of the alimentary tract were significantly higher in the full term group. Meanwhile, seleredema, respiratory distress syndrome, apnoea and respiratory failure were significantly higher in the premature group. When comparing clinical features, significant higher incidence of hemafecia was found in full term group while higher incidence of haematemesis, hypomyotonia and hypothermia was found in premature neonates group. Conclusions The risk factors and clinical features of NEC are different between full term infants and premature infants. Therefore it will be helpful for reducing the morbidity of NEC by preventing and treating high risk diseases and more attention should be paid to specific clinical features.
出处
《北京医学》
CAS
2009年第11期669-671,共3页
Beijing Medical Journal
