摘要
成骨细胞与材料复合构建组织工程化人工骨，有可能为治疗骨缺损提供一种新方法。这一技术的关键是为成骨细胞功能活动提供最佳环境。在总结了成骨细胞的细胞社会学特性之后，认为，理想的人工骨组成成份包括有机材料、无机材料及成骨细胞、血管内皮细胞等细胞成份，并含有最佳组合的生长因子缓释系统，植入体内能快速血管化，并形成大量骨组织修复缺损。
There is a great hope to treat long bone defects with bioactive artificial bone constructed by osteoblasts and biomaterials, in which the key point is to provide an optimum environment for the normal function of osteoblasts. The cellular sociological characteristics of osteoblasts were summarized and it was suggested that the ideal bioactive artificial bone should be composed of inorganic and organic materials together with cellular components such as osteoblasts and vascular endothelial cells, and combined with control release of growth factors, following its implantation it could be vascularized very soon and merged with the host bone by bony consolidation.
出处
《中国修复重建外科杂志》
CAS
CSCD
1998年第6期350-354,共5页
Chinese Journal of Reparative and Reconstructive Surgery
关键词
成骨细胞
细胞社会学
人工骨
Osteoblasts Cellular sociology Artificial bone
