摘要
目的探讨早期无创正压机械通气(NIPPV)治疗重症急性胰腺炎(SAP)合并急性肺损伤(ALI)患者的临床意义及应用价值。方法对本科收治的25例确诊SAP合并ALI患者在常规治疗的同时,早期辅以无创机械通气,记录患者血气分析、氧合指数、急性生理功能和慢性健康状况评分系统(APACHEⅡ评分)等资料。结果25例均成功脱机,器官功能改善,氧合指数上升,APACHEⅡ评分下降,无1例死亡,无1例进展成多器官功能障碍综合征(MODS)。结论无创正压通气提供了气道正压通气且无需气管插管或切开,较有创正压通气更易早期实施,能在早期改善患者低氧血症以及由低氧血症带来的一系列损害。
Objective To explore the therapeutic effects of early noninvasive positive-pressure ventilation in Severe Acute Pan- creatitis （SAP） with Acute Lung Injury （ALl）. Methods Twenty-five patients with SAP and ALI were treated by routine project and early noninvasive positive-pressure ventilation. During the therapy,blood gas analysis,PaO2/FiO2 and APACHE Ⅱ score were registered. Results All patients were evacuated ventilator successful,PaO2/FiO2 were raised, APACHE Ⅱ score was decline,no deaths, no one progress into MODS. Conclusion Noninvasive positive-pressure ventilation provide airway positive pressure ventilation and without tracheal intubation or cut, which is early and easy to implement, can improve the hypoxemia and the series of damages.
出处
《重庆医学》
CAS
CSCD
北大核心
2009年第20期2528-2529,共2页
Chongqing medicine
基金
重庆市卫生局医学科学技术研究资助项目(2008123)
关键词
无创正压通气
重症急性胰腺炎
急性肺损伤
noninvasive positive-pressure ventilation
Severe acute pancreatitis
acute lung injury
