摘要
目的:探讨了慢性前列腺炎患者治疗前后血清hs-CRP、IL-8和TNF-α水平的变化及意义。方法:应用放射免疫分析和免疫比浊法对32例慢性前列腺炎患者进行了治疗前后血清hs-CRP、IL-8和TNF-α检测,并与35名正常健康人作比较。结果:治疗前慢性前列腺炎患者血清hs-CRP、IL-8和TNF-α水平均非常显著地高于正常人组(P<0.01),经治疗2个月后则与正常人组比较无显著性差异(P>0.05)。结论:检测慢性前列腺炎患者血清水平的变化,可作为病情及预后评价的重要指标。
Objective To study the significance of changes of serum hs-CRP,IL-8 and TNF-α level after treatment in patients with chronic prostatitis.Methods Serum IL-8,TNF-α（with RIA） and hs-CRP（with immuoturbidty method） levels were determined in 32 patients with chronic prostatitis both before and after treatment as well as in 35 controls.Results Before treatment,the serum hs-CRP,IL-8 and TNF-α levels in the patients were significantly higher than those in controls（P〈0.01）.After treatment for 3 months,the levels in the patients were not much different from those in controls（P〉0.05）.Conclusion Serum hs-CRP,IL-8 and TNF-α content were closely related to the severity of chronic prostatitis and might be of prognostic significance.
出处
《放射免疫学杂志》
CAS
2009年第5期469-470,共2页
Journal of Radioimmanology
关键词
慢性前列腺炎
超敏C-反应蛋白
白细胞介素-8
肿瘤坏死因子-α
chronic prostatitis
high sensitive C-reactive protein（hs-CRP）
interleukin-8（IL-8）
tumor necrosis factor-α（TNF-α）
