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肺转移瘤立体定向放射治疗临床研究 被引量:1

Clinical Study of Lung Metastases Treated by Fractionated Stereotactic Radiotherapy
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摘要 目的:探讨体部立体定向放射治疗(X刀)肺转移瘤的方法和疗效。方法:采用CT模拟定位,拓能WiMRT体部立体定向放射治疗系统治疗肺转移瘤50例,病灶大小为1.0~5.0 cm。采用6 MV直线加速器,单次照射剂量5~12Gy,总剂量30~52 Gy。结果:肿瘤消失21灶(18.3%),缩小70灶(60.9%),总有效率79.1%;病灶<3 cm者,有效率为88.5%,明显高于病灶≥3 cm者(59.4%,P<0.05);总剂量≥40 Gy组的病灶消失率为26.4%,明显高于总剂量<40 Gy组(4.7%,P<0.01)。结论:体部X刀立体定向放射治疗是治疗肺转移瘤的有效方法。 Objective To explore the methods and effects of body fractionated stereotactic radiotherapy(X-knife) in the treatment of lung metastases.Methods There were 50 cases with lung metastases were treated by fractionated stereotactic radiotherapy using CT orientation and WiMRT model body X-knife.The diameter of the metastases was 1.0cm-5.0cm.The linear accelerator was 6Mv X-ray.The dose per fraction was 5-12Gy,and the total prescribed dose was 30-52Gy at the margin of the PTV enveloped by 90% insodose curve.Results The metastases complete regression was found 21 focus(18.3%)in CT image, partial regression in 70 focus (60.9%), and the overall effective rate was 79.1%. The effective rate for the focus with diameter less than 3era was 88.5%, and 59.4% equal or more than 3cm, there was significan differenee(P〈0.05).Conclusion Body fractionated stereotactic radiotherapy is an effective treatment method for lung metastases.
机构地区 解放军第
出处 《医疗卫生装备》 CAS 2009年第10期73-74,共2页 Chinese Medical Equipment Journal
关键词 肺转移瘤/放射治疗 立体定向放射治疗 疗效 lung metastases/radiotherapy fractionated stereotactic radiotherapy curative effect
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