摘要
白内障是严重影响人类健康的常见病、多发病。研究白内障的病因学及影响因素,是预防和治疗该病的有力措施。白内障主要是因晶状体的透光性改变所引发;晶状体的透光性是由晶体蛋白的有序结构所决定的。本文综述近年来有关晶体蛋白的组成与结构、翻译后修饰及热休克蛋白与白内障发病机制的关系。
Cataract is a common and frequently-occurring disease which seriously affects human health. The researches on the etiology of cataract and its influencing factors, are effective measures for the prevention and treatment of cataract. Occurrence of cataract is initiated by the crystal light-admitting quality change; the crystal ight-admitting quality is decided by the crystal ordered structure. This article summarized the relationship between related crystal protein composition and structure, posttranslational modification, heat shock proteins and cataract pathogenesis.
出处
《国际眼科杂志》
CAS
2009年第10期1923-1925,共3页
International Eye Science
基金
中国军队基金资助项目(No.2009ZXJ09004-063)~~
关键词
晶体蛋白
白内障
翻译后修饰
热休克蛋白
crystallin
cataract
post-translational modification
heat shock proteins
