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血液凝固过程压电响应机理研究及临床应用 被引量:3

Studies on Mechanism of Piezoelectric Responses in Blood Coagulation Process and Preliminary Clinical Application
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摘要 血液在压电晶体上的凝固,伴随晶体表面质量、粘弹性应力等性能的变化.由血凝各阶段的压电参数变化规律,和血凝过程的生化变化,并注意到压电传感最敏感部分为其电极表面,阐明了血凝三个阶段的复杂压电响应机理,提出了相应的压电传感方程,及从血凝压电特征曲线上提取血液流变学信息的方法.并初步应用于临床测试. A blood coagulation process is accompanied by characteristic changes of crystal surface mass,viscoelasticity and stress.According to the rules of variation of piezoelectric parameters,and noting the fact that the most sensitive part of a piezoelectric sensor is its electrode surface,the complicated mechanism of the piezoelectric responses was elucidated.The corresponding theoretical equations and the methods of drawing information of the hemorheology from the characteristic curves of the piezoelectric responses were proposed.The preliminary clinical application was showm.
出处 《湖南大学学报(自然科学版)》 EI CAS CSCD 1998年第5期34-37,共4页 Journal of Hunan University:Natural Sciences
基金 国家自然科学基金
关键词 血凝过程 压电响应 血液流变学 blood coagulation process,piezoelectric response,blood rheology
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参考文献3

  • 1周铁安,湖南大学学报,1998年,25卷,2期,23页
  • 2周铁安,博士学位论文,1990年
  • 3王力衡(译),薄膜,1983年

同被引文献24

  • 1罗阳,张雪,府伟灵.压电石英晶体传感器中的温度效应[J].重庆医学,2004,33(8):1138-1140. 被引量:3
  • 2陆斌,韦钰.基子全内反射萤光原理的免疫传感器[J].中国生物医学工程学报,1993,12(2):142-148. 被引量:26
  • 3Saigo M,Waters DD,Abe S,et al.Soluble fibrin,C-reactive protein,fibrinogen,factor Ⅶ,antithrombin,proteins C and S,tissue factor,d-dimer,and prothrombin fragment 1+2 in men with acute myocardial infarction≤45 years of age[J].Am J Cardiol,2004,94(11):1410-1413.
  • 4Turaj W,Slowik A,Dziedzic T,et al.Increased plasma fibrinogen predicts one-year mortality in patients with acute isehemic stroke[J].J Neurol Sci,2006,246(15):13-19.
  • 5Liu Y,Yin F,Long Y,et al.Study of the immobilization of alcohol dehydrogenase on Au-colloid modified gold electrode by piezoelectric quartz crystal sensor,cyclic voltammetry,and electrochemical impedance techniques[J].J Colloid Interface Sci,2003,258(1):75-81.
  • 6Zhou A,He D,Nie LH,et al.Determination of the binding parameters of drug to protein by equilibrium dialysis/piezoelectric quartz crystal sensor[J].Anal Biochem,2000,282(1):10-15.
  • 7Nomura T,Okuhara M.Frequency shift of piezoelectric quartz crystals immersed in organic liquids[J].Anal Chim Acts,1982,142(2):281-284.
  • 8Kanasawa KK,Gordon JG Ⅱ.The oscillation frequency of a quartz resonator in contact with a liquid[J].Anal Chim Acta,1985,175(9):99-105.
  • 9SHTxx数字温湿度传感器用户手册[EB/OL].Dalian Beifang M & C Ltd.Co.v2.01 March 2003.http://www.dabeco.com.cn
  • 10SHTxx数字温湿度传感器应用程序样例[EB/OL].Dalian Beifang M & C Ltd Co.http://www.dabeco.com.cn.

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