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联合用药治疗实验性外伤性增生性玻璃体视网膜病变 被引量:2

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摘要 目的:观察玻璃体腔注射曲安奈德和阿霉素治疗外伤性增生性玻璃体视网膜病变(PVR)的效果。方法:建立外伤性PVR动物模型。随机分为生理盐水组、曲安奈德组、阿霉素组、联合用药组。直接眼底镜观察PVR程度;酶联免疫吸附法(ELISA)测定玻璃体腔白介素-1β(IL-1β)、转化生长因子-β1(TGF-β1)浓度。结果:联合用药组PVR程度、玻璃体腔IL-1β、TGF-β1浓度低于生理盐水组。结论:玻璃体腔注射曲安奈德和阿霉素可降低PVR形成程度,下调玻璃体腔IL-1β、TGF-β1浓度。
出处 《实用医学杂志》 CAS 北大核心 2009年第20期3397-3399,共3页 The Journal of Practical Medicine
基金 广西自然科学基金资助项目(编号:桂科自0640191)
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