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脑梗死患者颈动脉斑块与胆红素和纤维蛋白原水平的研究

Association of carotid plaque with serum bilirubin levels and fibrinogen level in patients with cerebral infarction
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摘要 目的:研究脑梗死患者颈动脉粥样斑块与胆红素和纤维蛋白原之间的关系。方法:对110例脑梗死住院患者通过颈动脉多普勒超声确定有无颈动脉斑块,根据斑块的有无分为斑块组(72例)和无斑块组(38例)。2组之间性别、年龄比较无显著差异(P>0.05)。同时测定胆红素和纤维蛋白原水平,调查血糖、血脂及高血压等其他危险因素。结果:斑块组血胆红素,尤其是间接胆红素明显低于无斑块组,有统计学意义(P<0.05),纤维蛋白原明显高于无斑块组,有统计学意义(P<0.05)。结论:低血清胆红素、高纤维蛋白原水平为颈动脉斑块形成和发展的重要危险因素。 Objective:To study the relationship between carotid plaque and serum bilirubin and fibrinogen in the patients with cerebral infarction. Method: 110 in-patients with cerebral infarction were screened for carotid plaque by duplex color Doppler, and then classified into plaque group (n=72) and non-plaque(n=38) groups. No statistical difference in age and gender existed between the 2 groups and in the mean time, the serum bilirubin and fibrinogen were measured, and other possible risk factors for stroke such as serum lipids and glucose, hypertension were investigated. Result: TBIL,IBIL were significantly lower ( P 〈0.05) and FIB was significantly higher ( P 〈0.05)in carotid plaque patients than non-plaque groups. Conclusion: The lower serum bilirubin and the high fibrinogen,are important risk factors for predicting carotid plaque with cerebral infarction.
出处 《临床急诊杂志》 CAS 2009年第5期274-275,共2页 Journal of Clinical Emergency
关键词 脑梗死 动脉粥样硬化 胆红素 纤维蛋白原 cerebral infarction carotid plaque bilirubin fibrinogen
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