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乳腺癌微淋巴管形成因素的研究进展

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摘要 研究表明,乳腺癌的转移与癌周微淋巴管的形成有关,且认为微淋巴管的形成是一多因子、多网络参与调节的复杂过程。在影响其调控的诸因子中,血管内皮生长因子(VEGF)及其受体起着关键的作用,前列腺素内源性过氧化物合成酶和一氧化氮在调控的过程中能起到促进VEGF生成的作用,另外趋化因子及其受体及胸苷磷酸化酶也被证实影响着微淋巴管的形成。各因子在微淋巴管的形成过程中互相影响,彼此促进。
出处 《临床外科杂志》 2009年第7期494-495,共2页 Journal of Clinical Surgery
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