摘要
目的探讨米非司酮治疗子宫肌瘤的临床效果。方法我院2002年6月-2006年3月收治子宫肌瘤患者54例，给予口服米非司酮10mg，1次／天，连服90天为一疗程，应用彩色超声监测治疗前后子宫肌瘤变化，测定肝、肾功能，血红蛋白，观察服药后的不良反应。结果54例患者服药期间均出现闭经，贫血症状均得到改善，治疗后子宫及肌瘤体积均缩小（p〈0．05），雌激素及孕激素水平均下降（P〈0．01）。服药早期出现消化道不适，1周后症状消失，未见肝肾功能改变。结论米非司酮治疗子宫肌瘤安全、有效、经济、副反应小，特别适合基层医院推广使用。
Objective To observe the application of the drug mifepristone treatment the clinical effects of uterine fibroids. Methods 56 cases of uterine myoma in patients with oral mifepristoue 10 rag, 1 times / d, even serving 9 0 d for one course of treatment, the application of color Doppler monitoring before and after treatment of uterine leiomyoma Change, determination of liver and kidney function, hemoglobin observed adverse reactions after medication, Results 56 patients with medication both during amenorrhea, symptoms of anemia were improved after treatment of uterine and fibroid volume were narrowing （P〈 0.05）, estrogen and progesterone drop of water on average （P〈 0.01）. Medication early gastrointestinal discomfort, one week after symptoms disappear, no changes in Liver and kidney functions. Coneluaions The clinical effects of mifepristone treatment of uterine leiomyomas have a certain effect, is a safe, effective, economic, and treatment of minor side effects, especially suitable for grass-roots hospitals.
出处
《国际医药卫生导报》
2009年第17期54-57,共4页
International Medicine and Health Guidance News
关键词
子宫肌瘤
米非司酮
治疗
Hysteromyoma
Mifepristone
Treatment
