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心血管事件年和日周期节律的临床研究 被引量:3

A study on yearly and daily circadian rhythm of cardiovascular events
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摘要 目的探讨心血管事件的年和日周期节律。方法记录10年间5837例急诊患者心血管疾病事件发生的时间和月平均气温,分析月平均气温与心血管事件的关系。结果急性心肌梗死、心绞痛、急性左心衰竭、高血压危象、猝死以冬春寒冷季节及季节交替时发病率最高,发病率与月平均气温显著负相关(P〈0.005~0.001)。清晨和上午心血管事件发病率较高。结论心血管事件的发生具有明显的年和日周期节律;寒冷是心血管事件的重要危险因素,清晨和上午为发病的高峰时段。 Objective To investigate the circadian and seasonal distribution of cardiovascular events (CVE) and the relationship between average monthly temperature and the incidence of CVE. Methods A total of 5837 emergency patients with CVE were enrolled from 1997 to 2007. The exact admission time of each patient was registered. The average monthly temperature data from a regional weather station for this time period was supplied by the meteorological office of the city. The relationship between the average monthly temperature and the incidence of CVE was explored and the corresponding curves were plotted. Results The occurrence of CVE has obvious seasonal variation, and its a higher tendency of episodes was found in spring and winter periods. High incidence of acute myocardial infarction, angina pectoris, acute left-sided heart failure, hypertensive crisis, and sudden death occurred in spring and winter as well as the time for a change of season, that is, January, February, March, April, October, November, and December. There was a significant negative correlation between the incidence and the average monthly temperature (P 〈0. 005-0. 001 ). Circadian rhythm of CVE was present, with a peak in the early morning and forenoon. Conclusion There are circadian and circannian rhythms of the incidence of CVE. Cold weather condition is a risk factor for the occurrence of CVE, which usually peaks in the early morning and forenoon.
出处 《中华内科杂志》 CAS CSCD 北大核心 2009年第10期818-820,共3页 Chinese Journal of Internal Medicine
关键词 天气 季节律 心血管疾病 Weather Season rhythm Cardiovascular diseases
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参考文献11

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