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中国胃肠道间质瘤诊断治疗共识 被引量:101

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摘要 胃肠道间质瘤(gastrointestinal stromal tumors,GIST)是胃肠道最常见的间叶源性肿瘤,免疫组织化学染色大多数呈CD117阳性。传统放疗和化疗对GIST几乎无效。酪氨酸激酶抑制剂甲磺酸伊马替尼的临床应用使GIST的治疗发生了重大的改变,为部分晚期GIST患者带来了延长生存期的疗效。同时由于对GIST基因突变认识的进一步提高,使GIST的诊断率显著提高。为了规范GIST的诊断和临床治疗,建立包括病理科、放射科、胃肠外科和肿瘤内科医师的多学科合作网络,乃至建立GIST治疗中心是必要的。
出处 《中华病理学杂志》 CAS CSCD 北大核心 2009年第10期697-702,共6页 Chinese Journal of Pathology
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