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梅毒螺旋体抗体特异性与非特异性试验的评价 被引量:4

Comparation between spirochaeta pallida antibody specificity and non-specificity test
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摘要 目的比较和评价TP-ELISA、TRUST、TPPA等梅毒检测法。方法采用TP-ELISA及TRUST法同时筛查6988例患者标本中的梅毒指标,阳性结果采用TPPA法确证。结果在TPPA法确证的368例阳性标本中,TRUST检出270例,符合率为71.05%,TP-ELISA检出380例,符合率为100%,TRUST符合率明显低于TP-ELISA法。结论TP-ELISA试剂的敏感性远远高于TRUST试剂,无论哪种试剂阳性均应进行TPPA确证。由于试剂较贵,操作较繁琐,不利于批量检测,所以无法直接采用TPPA法。 Objective To compare the TP-ELISA, TRUST, TPPA of syphilis testing.Methods TP-ELISA and TRUST methods were used to screen patients with syphilis,the results were confirmed by TPPA law. Results Among 368 cases of TPPA positive samples, TRUST confirmed 270 cases, the rate was 71.05%, TP-ELISA detected 380 cases, the rate of coincidence Was 100% ,TRUST was significantly worse than TP-ELISA. Conclusion The sensitivity of TP-ELISA was far higher than that of TRUST, no matter what regent was positive, we need TPPA to confirm. Because regents were expensive and the test was complicated, which was unfit for batch test, TPPA could not be used directly.
出处 《基层医学论坛》 2009年第28期915-917,共3页 The Medical Forum
关键词 梅毒检测 TP-ELISA TPPA TRUST Syphilis testing TP-ELISA TPPA TRUST
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