摘要
目的探讨纤维蛋白胶固定球结膜移植片的效果和安全性。方法采用前瞻性随机对照的方法。对40例原发性鼻侧翼状胬肉行翼状胬肉切除联合自体角膜缘干细胞移植术,术中分别采用纤维蛋白胶(20例,20眼)和10-0尼龙缝线(20例,20眼)固定球结膜移植片,术后随访6个月。结果两组手术移植的球结膜瓣均成功固定于巩膜表面,并全部成活。纤维蛋白胶组患者平均手术时间(20.5±3.6)min,10-0尼龙缝线组平均手术时间(42.8±4.5)min(P<0.01)。术后纤维蛋白胶组患者疼痛、异物感、畏光、流泪症状比缝线组轻并消失较快(P<0.01)。随访期间两组均无复发。结论翼状胬肉切除后使用纤维蛋白胶粘贴固定自体球结膜瓣是一种安全、有效的方法。
Objective To study the clinical value of fibrin glue on attaching conjunctival autografts after pterygium excision. Methods Prospective, randomized comparison method was adopted. Forty patients with primary pterygium were randomly divided into the fibrin glue group （20 eyes ） and the 10-0 nylon suture group （20 eyes ） A superior conjunctival autograft was harvested and transferred onto bare sclera after pterygium excision. Fibrin glue was used to attach the autograft in 20 eyes and nylon 10-0 su- ture was used to attach the autograft in 20 eyes. The patients were followed up for 6 months. Results All conjunctival autografts in both groups were successfully attached and were intact without falling off, dissolution or recurrence after 6 months. The mean surgical duration was（20. 5 ± 3.6） minutes for the fibrin glue group and （42.8 ±4.5 ） minutes for the suture group. The mean surgical duration was significantly shorter in the fibrin glue group（ P 〈 0.01 ）. Subjective symptoms of pain, foreign body sensation, tearing, and photophobia were milder and disappeared more rapidly in the fibrin glue group. （ P 〈 0.0 i ）. Conclusion Fibrin glue is a safe and effective method for attaching conjunctival autografts after pterygium eXCISIOn.
出处
《眼外伤职业眼病杂志》
2009年第9期699-702,共4页
Journal of Injuries and Occupational Diseases of the Eye with Ophthalmic Surgeries
