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丝裂霉素及调整缝线在小梁切除术中的应用 被引量:7

Trabeculectomy combined with mitomycin C and adjustable suture
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摘要 目的探讨复合小梁切除术的降眼压效果。方法对58例(78眼)青光眼实施复合小梁切除术,术中在巩膜瓣下放1块0.25 mg/mL丝裂霉素C浸润棉片3 min。缝合巩膜瓣时增加缝线跨距以备术后断线控制眼压。术后随访眼压、滤过泡及前房情况。结果全部患眼手术成功,滤过泡形成满意,在术后1周、1月、3月、及6月时眼压控制良好,与术前比P<0.001。6月时滤过泡均为有功能的滤过泡。并发症主要有早期浅前房、少量前房积血等。结论术中使用0.25 mg/mL丝裂霉素C有利于形成长期有效的滤过泡,结合术后断线可更好地控制眼压,减少浅前房等并发症的发生。 Objective To discuss the effect of trabeculectomy combined with mitomycin C and adjustable suture. Methods 78 eyes of 58 patients with glaucoma were under combined-trabeulectomy with one piece of 0.25mg/ml mitomycin C soaked cotton lobe under scleral flap for 3minites during surgery. In suturing scleral flap tire stitch span were increased in order that it would be easy to cut off for IOP control. Postoperative lOP, conditions of filtered bubble and anterior chamber were followed up for 6 months. Results All patients were successfully underwent combined-trabeulectomy to form content filtered bubble. During 6 months follow up, the IOP were effectively controlled, hy student's t test p 〈 0. 001. The main complication were early stage shallow anterior chamber and minimal hyphema. Conclusion The use of 0.25 mg/mL mitomycin C during surgery is profit to get long-term effectual filtered bubble. Combined with broken the scleral suture, the lOP control will be more ideal and decreased the side effect such as shallow of anterior chamber.
出处 《眼外伤职业眼病杂志》 2009年第9期683-684,共2页 Journal of Injuries and Occupational Diseases of the Eye with Ophthalmic Surgeries
关键词 青光眼 小梁切除术 丝裂毒素C 高速缝线 glaucoma trabeculectomy mitomycin C adjustable suture
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