期刊文献+

低分子肝素治疗不稳定型心绞痛疗效观察

原文传递
导出
摘要 目的:观察低分子肝素在不稳定性心绞痛治疗中的有效性及安全性。方法:168例不稳定性心绞痛患者随机分为两组,对照组和治疗组,治疗组在常规治疗下加用低分子肝素。结果:从心绞痛发作次数,持续时间,疼痛程度,心电图改善比较治疗组明显优于对照组,有统计学差异(P<0.05)总有效率83.7%。结论:低分子肝素是治疗不稳定性心绞痛安全有效的抗血栓形成药。
作者 王彦华
出处 《中国误诊学杂志》 CAS 2009年第27期6573-6573,共1页 Chinese Journal of Misdiagnostics
  • 相关文献

参考文献2

二级参考文献14

  • 1周巧玲,张阳德,保元裕一郎,野崎刚.肝素对人类系膜细胞金属基质蛋白酶1、3表达的影响及其肾保护作用[J].中国现代医学杂志,2005,15(21):3212-3215. 被引量:4
  • 2林平,林英,王晓红.低分子肝素[J].临床军医杂志,2006,34(5):630-632. 被引量:27
  • 3Bergonzini G. 01igo-Heparin Action on Endogenous Glycosaminoglycans. Pharmacokinetics :Direct and Mediated Effects [J]. Semin Thromb Hemost, 1994,20(3) : 274.
  • 4Wan MX, Zhang XW, Torkvist L, et al. Low molecular weight hearin inhibits tumor necrosis factor alphainduced leukocyte rolling[J]. Inflamm Rex,2001,50(12) :581.
  • 5Jones H, Paul W, Page CP. The effects of heparin and related moleles on vascular permeability and neutrophil accumulation in rabbit skin[J]. Br J Pharmacol, 2002,135 (2) : 469-479.
  • 6Wang L, Brown JR,Varki A,et al. Heparin's anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L-and P -selectins [J ]. J Clin Invest, 2002, 110 ( 1 ) : 127-136.
  • 7Burg M, Ostendorf T, Mooney A, Koch KM, and Floege J : treatment of experimental mesangioproliferative glomerulonephritis with nonanticoagulant heparin: Therapeutic efficacy and safety [J]. Lab In-vest,1997,76:505-516.
  • 8Ottlinger ME,Pukac L,Karnovsky MJ..Heparin inhibits mitogen activated protein kinase activation in intact rat vascular smooth muscle cells[J]. J Bio Chem, 1993,268 : 19173.
  • 9Peten EP, He CJ, Patel A, et al. Non-anticoagulan heparin suppresses al collagen MRNA and reduces laminin B1 Mrna expression in sclerotic glomeruli from mice transgenic for growth hormone(GH)mice (abstract)[J]. J AM Soc Nephrol, 1993,4:780.
  • 10Mattana J,Singhal PS:Heparin attenuates the effect of mitogenic vasoconstrictors on mesangial cell proliferation and handling of immunoglobulin Gcomplexes[J]. J Pharmacol Exp Ther, 1995, 273:80.

共引文献108

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部