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慢性乙型重型肝炎患者医院感染特点与控制措施 被引量:6

Hospital Infection in Patients with Chronic Severe Hepatitis B:Distribution Characteristics and Control Measures
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摘要 目的探讨慢性乙型重型肝炎患者医院感染的发病率,好发部位及危险因素,寻求有效的控制措施。方法对2001年1月-2007年12月收治的466例慢性乙型重型肝炎患者的医院感染状况进行调查分析。结果466例慢性乙型重型肝炎患者发生医院感染例次率为20.1%,感染部位下呼吸道56例次占59.6%,上呼吸道17例次占18.1%,菌血症7例次占7.4%,泌尿道3例次占3.2%,胃肠道7例次占7.4%,皮肤软组织1例次占1.1%。结论必须加强肝病科医护人员对医院感染危险因素的认识,严格掌握抗菌药物的使用原则,掌握无菌操作,加强标准预防的理念,积极治疗原发病,才能有效降低医院感染的发生。 OBJECTIVE To investigate and control the risk factors about hospital infection in patients with chronic severe hepatitis B. METHODS Totally 466 hospitalized patients with chronic severe hepatitis B in our hospital from Jan 2001 to Dec 2007 were studied retrospectively. RESULTS The total incidence of hospital infection was 20.1 for inpatients with chronic severe hepatitis B, the infection located as follows:56 patients were in lower respiratory tract (59.6%);17 patients in upper respiratory tract (18.1%) ; 7 patients with bacteremia (7.4%) ;3 patients in urinary tract (3.2%) ; 7 patients in gastrointestinal tract (7.4%) ; and 1 patients was in cutis tissue (1. 1%). CONCLUSIONS The knowledge about the on infection risk factors liver disease must be strengthened by hospital medical staff of the use of antibiotics must be strict controlled in principle, operation must be aseptic, the concept of prevention standards must be enhanced, and the primary disease must be actively treated, all these can effectively reduce infection in hospital.
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2009年第18期2434-2435,共2页 Chinese Journal of Nosocomiology
关键词 慢性乙型重型肝炎 医院感染 回顾性调查 控制措施 Chronic severe hepatitis B Hospital infection Retrospective investigation Control measures
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  • 1晏春根,谢青,周霞秋,徐玉敏,俞红,郭清.暴发性肝衰竭中Toll样受体2表达的实验研究[J].中华肝脏病杂志,2004,12(9):549-551. 被引量:7
  • 2邓敏,刘磊.老年肝病患者医院感染特点及相关危险因素的研究[J].中华医院感染学杂志,2004,14(11):1234-1236. 被引量:6
  • 3陈然峰,陈国军,董长林,黄晓文,陈孟春.乙型肝炎复制与感染指标的相关性及各指标在肝病防治中的应用[J].中华医院感染学杂志,2004,14(10):1084-1086. 被引量:18
  • 4Notlte FS, Kwok S, Higuchi R, et al. Avoiding false positives with PCR[J]. J Clin Microbiol, 2003,41:1558-1564.
  • 5Kidd-Ljunggren K, Grandjacquesc P, Pradat P, et al. Rapid detection of genotypes and mutations in the pre-core and the pre-core region of hepatitis B virus genorne[J]. J Gen Virol,1997,78 : 1469-1478.
  • 6Sumi H, Yokosuka O, Seki N, et al. Influence of hepatitis B virus genotypes on the progression of chronic type B liver disease[J]. Hepatology, 2003,37 : 19-26.
  • 7.医院感染诊断标准(试行)[S].[S].中华人民共和国卫生部,2001.2..
  • 8Kristich CJ, Li YH, Cvitkovitch DG, et al. Esp-independent biofilm formation by Enterococcus faecalis [J]. J Bacteriol,2004, 186(1): 154-163.
  • 9Toledo-Arana A, Valle J, Solano C, et al. The enterococcal surface protein, Esp, is involved in Enterococcus faecalis biofilm formation[J]. Appl Environ Microbiol, 2001, 67 (10):4538-4545.
  • 10Nallapareddy SR, Singh KV, Duh RW, et al. Diversity of ace,a gene encoding a microbial surface component recognizing adhesive matrix molecules, from different strains of Enterococcs faecalis and evidence for production of ace during human infections[J]. Infect Immun, 2000, 68: 5210-5217.

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  • 1何强,康志敏,王芳,张渊,王莉.实施感染防治措施对血液透析乙肝及丙肝病毒感染控制的效果观察[J].实用医院临床杂志,2010,7(4):49-51. 被引量:16
  • 2何国伟,范红顺,范艳萍.重型肝炎继发医院感染156例临床分析[J].实用医技杂志,2007,14(1):92-93. 被引量:7
  • 3王晓东,金若珏,金益辉,朱碧红,郑波,欧阳钦.重型肝炎患者肠球菌属感染112例临床特征及转归[J].中华医院感染学杂志,2007,17(4):406-409. 被引量:4
  • 4中华医学会传染病与寄生虫病学分会 肝病学分会.病毒性肝炎防治指南.中华传染病杂志,2001,19:56-62.
  • 5张群,付志仁,蔡剑飞,唐晓峰,彭洁洁.肝移植后真菌感染易感因素分析[J].微生物与感染,2007,2(2):99-101. 被引量:3
  • 6National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial susceptibility testing [S] M100-S12. NCCLS,2002:21.
  • 7Takkenberg RB, Weegink CJ, Zaaijer HL, et al. Newdevelopments in antiviral therapy for chronic hepatitis B [J]. VoxSang,2010,98(4) :481-494.
  • 8Raptopoulou M, Papatheodoridis G, Antoniou A, etal. Epidemiology,course and disease burden of chronic hepatitis Bvirus infection. HEPNET study for chronic hepatitis B: amulticentre Greek study [J]. J Viral Hepat, 2009, 16(3) : 195-202.
  • 9Sheu LC, ToyBC, Kwahk E, et al. A model for interprofessionalhealth disparities education ? student-led curriculum on chronichepatitis B infection [ J]. J Gen Intern Med,2010,25 ( Suppl 2):S140-145.
  • 10Stefos A, Gatselis N, Zachou K,et al. Descriptive epidemiology ofchronic hepatitis B by using data from a hepatitis registry in CentralGreece [J]. Eur J Intern Med,2009 ,20( 1 ) :35-43.

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