摘要
目的:评价小剂量舒芬太尼复合丙泊酚静脉麻醉在无痛人流术中的疗效和安全性。方法:选择自愿行人工流产术的患者80例,ASAⅠ～Ⅱ级妊娠4～8周,随机分为两组(每组40例)。观察组(A组):0.1μg/kg舒芬太尼复合丙泊酚进行人工流产术麻醉;对照组(B组):单纯应用丙泊酚进行人工流产术麻醉。观察MAP、HR、SpO_2,记录丙泊酚的总剂量、意识恢复和定向力恢复时间、术中呼吸抑制和术后宫缩痛(采用VAS评分)的发生率。结果:B组MAP、HR及SpO_2略有下降;A组MAP无明显变化,HR和SpO_2均明显下降(P<0.05);A组丙泊酚总用量及意识恢复时间、定向力恢复时间均低于B组(P<0.05)。结论:小剂量的舒芬太尼(0.1μg/kg)复合丙泊酚用于无痛人工流产术的麻醉,减少了丙泊酚的总用药量和呼吸循环抑制的发生,非常有效地减轻患者术后宫缩痛,缩短苏醒时间使麻醉更加平稳。
Objective： To evaluate efficacy and safety of low-dose sufentanil as supplement to propofol anaesthesia in pain-less abortion. Methods： 80 ASA Ⅰ～Ⅱ pregnant women they 4-8 weeks of pregnancy undergoing painless abortion were randomly divided into composite application of low-dose （0.1 μg/kg） sufentanil group （A group） （n=40） and Propofol group （B group） （n =40）. To abserve MAP, HR, SpO2 and take notes propofol dosage, recovery time of consciousness and directional, intraoperative respirative depression and postoperative pain in the incidence of uterine （use VAS score）. Results： Slightly declining of MAP, HR and SPO2 in group B. No obvious diversification of MAP in group A, HR and SPO2 have both declined distinctly （P〈0.05）. The total consumption of propofol, recovery time of consciousness and directional in group A are much more lower than those in group B （P〈0.05）. Conclusion： Low dose sufentanil combined with propofol can reduce propofol dosage, respiratory, circulatory inhibition rat and shorten the recovery time, make the anesthesia process smooth.
出处
《新疆医科大学学报》
CAS
2009年第8期1161-1162,共2页
Journal of Xinjiang Medical University
关键词
舒芬太尼
丙泊酚
人工流产
sufentanil
propofol
painless abortion
