摘要
目的了解南昌市西湖区糖尿病(DM)的患病率及相关危险因素。方法于2006年10月—2007年9月对江西省南昌市西湖区十字街办辖区20岁以上常住居民进行抽样调查。主要内容包括流行病学问卷调查(询问DM家族史,既往DM史)、体格检查和实验室检查(空腹及餐后2h血糖、糖化血红蛋白、血脂等)。结果1494名调查者中,DM和糖调节受损的标准化患病率分别为8.4%和6.4%,DM患者174例,糖调节受损97例,新诊断的DM患者占全部DM患者的44.3%。多因素分析结果显示,男、女性增龄(OR值分别为1.05、1.09、P值均<0.001)、男、女性有DM家族史(OR值分别为3.74、4.49,P值均<0.001)、高三酰甘油(OR值分别为1.19、1.21,P值分别为0.009、0.028)、男性腰围(OR=1.06,P<0.001)或百分体脂含量增高(OR=1.08,P=0.003)和女性高密度脂蛋白水平降低(OR=0.23,P=0.004)均可增加DM的患病危险。男性适量饮酒可降低DM的患病危险(OR=0.54,P=0.037)。结论南昌市西湖区有较高的DM患病率,相当一部分人群患DM后不后能及时诊断。增龄、DM家族史、肥胖、血脂异常是患DM的危险因素。
Objective To investigate the prevalence of diabetes mellitus（DM） and the risk factors in Xihu District of Nanchang. Methods During Oct. 2006--Sep. 2007, a cross-sectional study was conducted with 1 494 individuals （aged 20 years or over） who lived in Xihu District. The study included epidemiological questionnaires （DM history and family history）, physical examination and laboratory detection （fasting and 2hPG）. Results In the ｜ 494 individuals, the number of newly diagnosed DM, IR were 174 and 121, respectively. The standardized prevalences of DM and Impaired glucose tolerance （IFT） were 8.4% and 6.4%, repectively. Multivariable logistic regression analysis showed that the family history of DM （male, OR =3.74, P〈 0. 001 ; female, OR = 4.49, P〈0. 001）, aging（male, OR= 1.05, P〈0.001; female, OR= 1.09, P〈0.001）, high level of triglyceride（male, OR = 1.19, P = 0. 009 ; female, OR = 1.21, P = 0. 028）, waist circum （ WC, OR = 1.06, P〈 0.001 ） or percentage of body fat （BF %, OR = 1.08, P = 0. 003） in male, and low level of HDL-cholesterol（ OR = 0.23, P = 0. 004）all increased the risk of DM. In additional, proper amount of alcohol intake （ OR = 0.54, P = 0. 037） in male decreased the risk of DM. Conclusion The prevalence of DM is high in Xihu District of Nanchang. Family history of DM, aging, obesity and lipid abnormality are the risk factors of DM.
出处
《上海医学》
CAS
CSCD
北大核心
2009年第8期720-724,共5页
Shanghai Medical Journal
基金
江西省卫生厅资助项目(20062038)
江西省南昌市科学技术委员会重点攻关资助项目
关键词
糖尿病
患病率
危险因素
Diabetes mellitus
Prevalence
Risk factor
