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卡维地洛联合缬沙坦对心肌梗死合并心力衰竭患者左心室重塑及左心室功能的影响 被引量:5

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摘要 目的观察卡维地洛联合缬沙坦治疗心肌梗死合并心力衰竭对患者左室功能和左室重塑的影响。方法选择心肌梗死合并心力衰竭患者60例,随机分为卡维地洛联合缬沙坦治疗组(A组)和单纯缬沙坦治疗组(B组),每组30例,随访12个月,观察心功能指标和血浆脑钠肽(BNP)浓度的变化。结果2组随访期无死亡,2例分别因心力衰竭加重和心绞痛发作再次住院。治疗组于治疗后左心室射血分数(LVEF)增加(P<0.05),左室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)、室间隔厚度(IVSD)缩短(P<0.05),血浆脑钠肽浓度降低(P<0.05)。结论长期应用卡维地洛联合缬沙坦可明显改善心肌梗死患者心功能,防止心肌重塑,其作用优于单纯使用缬沙坦治疗。
出处 《河北医药》 CAS 2009年第18期2428-2429,共2页 Hebei Medical Journal
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