摘要
目的探讨影响小肝癌手术疗效的相关问题。方法回顾性分析８年间手术切除的８２例瘤径≤５０ｃｍ的小肝癌。其中ＨＢｓＡｇ（＋）６０例，合并肝硬变７１例。７８例肝细胞癌的高、中、低分化分别为１５、５３和１０例。行联合肝段切除１３例，肝段切除１４例，局部肝切除５５例。结果手术病死率为１２％，术后１、３、５年生存率分别为９２７％、７２５％、５４３％。高、中、低分化组术后５年生存率分别为７９６％、４９９％和４１１％。术后１、３、５年复发率分别为１２８％、４０７％、７１５％。结论小肝癌具有与大肝癌相同的肝病史，早期发现和限量肝切除是减少术后并发症、提高术后生存率的重要途径。
Objective To determine which clinicopathologic features and surgical modalities are related to the prognosis of small primary liver cancer(SPLC). Method Eighty-two patients who had under gone operations for SPLC(≤50cm in diameter) from 1988 to 1995 were retrospectively studied.60 patients were HBsAg positive, and 71 patients suffered from liver cirrhosis. Bisegmentectomy, segmentectomy and partial resections were performed in 13, 14 and 55 patients separately. Result The overall operative mortality was 12%,and the 1, 3, 5year survival rates were 927%, 725% and 543%, respectively. The 5year survival rates of 78 patients with hepatocellular carcinoma according to histologic features were 796%, 499% and 411% in welldifferentiated (15 patients), moderately (53), and poorly differentiated (10) groups. Recurrence and metastasis rates in 1, 3, 5 years were 128%, 407% and 715%, separately. Conclusion SPLC has the same history of large PLC. Early diagnosis and limited hepatic resection are very importent to decrease the mortality and increase the survival rate.
出处
《中华外科杂志》
CAS
CSCD
北大核心
1998年第8期451-453,共3页
Chinese Journal of Surgery
