摘要
Objective To assess the effects of sleep deprivation (SD) on the whole night polysomnography (PSG) in healthy young men. Methods The whole night PSG was recorded by using Neurofax-1518K (Nihon Kohden, Japan) system before and after 38 h of SD among 15 healthy male subjects. Results Compared with PSG before SD, post-SD PSG showed significantly shortened sleep latency (before SD: 19.7±9.3, after SD: 5.6±7.3, P<0.05), decreased stage 1 (S1) non-rapid eye movement (NREM) sleep [before SD: (9.2±1.9)%, after SD: (4.0±1.4)%, P<0.05], and increased stage 4 (S4) NREM sleep [before SD: (10.3±3.7)%, after SD: (26.2±4.3)%, P<0.01]. Conclusion During post-SD sleep, the proportion of S4 NREM sleep was increased as compensation in healthy male. In addition, SD was proved to affect electrophysiological brain activities in normal people.
Objective To assess the effects of sleep deprivation （SD） on the whole night polysomnography （PSG） in healthy young men. Methods The whole night PSG was recorded by using Neurofax-1518K （ Nihon Kohden, Japan） system before and after 38 h of SD among 15 healthy male subjects. Results Compared with PSG before SD, post-SD PSG showed significantly shortened sleep latency （before SD. 19.7 ± 9. 3, after SD： 5.6± 7.3, P 〈 0. 05 ） , decreased stage 1 （ S1 ） non-rapid eye movement （NREM） sleep [ before SD： （ 9. 2 ± 1.9 ） % , after SD： （4.0 ± 1.4 ） %, P 〈 0. 05 ], and increased stage 4 （ S4 ） NREM sleep [ before SD ： （ 10. 3 ± 3.7 ） %, after SD ： （ 26. 2 ± 4. 3 ） %, P 〈 0. 01 ]. Conclusion During post-SD sleep, the proportion of S4 NREM sleep was increased as ＂ compensation＂ in healthy male. In addition, SD was proved to affect electrophysiological brain activities in normal people.
基金
Supported by National High Technology Research and Development Program of China (863 Program, No.2007AA02Z420 and No.2008AA02Z412)
Joint Key Project of New Frontier Technology in Shanghai Municipal Hospitals (No.SHDC12006105)
Foundation of the National Natural Science Foundation of China (No.30770772)
the Municipal Committee of Shanghai Science and Technology (No.09411968200)
