摘要
目的观察代谢综合征患者尿微量白蛋白(MAU)与颈动脉粥样硬化的关系。方法328例住院患者分为代谢综合征组(MS组,176例)和非MS组(152例)。比较两组患者尿微量白蛋白的变化及颈动脉超声检测结果。结果MS组BM I、SBP、DBP、脉压差、TG、LDL-C、Hs-CRP、MAU阳性率、IMT及颈动脉内径均显著高于非MS组;MAU阳性组IMT、颈动脉内径显著高于MAU阴性组,斑块指数两组之间差异无统计学意义。MS组中IMT及颈动脉内径在尿微量白蛋白阴性组中较阳性组差异有统计学意义,但斑块指数两组间差异无统计学意义。结论MAU阳性患者易出现颈动脉粥样硬化,MS患者中这种变化比无中心型肥胖的高血压、糖尿病和高血脂患者更为明显。
Objective To observe the relationship between microalbunminuria （MAU） and carotid atherosclerosis in patients with metabolic syndrome. Methods A total of 328 inpatients were divided into two groups ： metabolic syndrome group （ MS group, 176 cases） and non-MS group （152 cases）. Comparison of microalbunminuria level and carotid artery ultrasound resuits in patients of 2 groups was conducted. Results The BMI, SBP, DBP, pulse pressure, TG, LDL-C, Hs-CRP, MAU- positive rate, IMT and carotid artery diameter of MS group were significantly higher than those of non-MS group. IMT and carotid artery diameter were significantly higher in MAU-positive group than in MAU-negative group, while no difference was found in plaque index between the two groups. Significant differences in IMT and carotid artery diameter as well as non-significant difference in plaque index were found between MAU-positive and negative patients in MS group. Conclusion MAU-positive patients are prone to carotid atherosclerosis, especially in those complicated with MS compared with those without central obesity related hypertension, diabetes and high blood cholesterol.
出处
《中国预防医学杂志》
CAS
2009年第8期710-712,共3页
Chinese Preventive Medicine
