前列腺癌患者尿液DD3mRNA表达及其意义的研究进展
摘要
随着前列腺癌在老年男性中的发病率的升高,早期诊断对其治疗及预后评价有着重要意义。DD3是近年来发现的在前列腺癌细胞特异性表达的一种新的肿瘤标志物,与传统的肿瘤标记物(如PSA等)相比具有更高的敏感性和特异性。对前列腺癌患者进行尿液DD3检测为一种既方便又理想的方法,本文对该方面的研究进展进行了综述。
出处
《国际泌尿系统杂志》
2009年第5期608-611,共4页
International Journal of Urology and Nephrology
参考文献26
-
1Bussemakers MJG, van Bokhoven A, Vethaegh GW, et al. DD3: A new prostate - specific gene, highly overexpressed in prostate cancer. Cancer Res. J Cancer Res, 1999,59:5975 - 5979.
-
2Seitz C, Palermo S, Djavan B. Prostate biopsy. Minerva. J UrolNefrol 2003,55:205 -218.
-
3Raja J, Ramachandran N, Munneke G, Patel U. Current status of transrectal ultrasound - guided prostate biopsy in the diagnosis of prostate cancer. J Clin Radiol 2006,61 : 142 - 151.
-
4de Kok JB, Verhaegh GW, Roelofs RW,et al. DD3(PCA3), a very sensitive and specific marker to detect prostate tumors. J Cancer Res, 2002,62:2695 - 2698.
-
5Schalken J, Hessels D, Verhaegh G. New targets for therapy in prostate cancer: differential display code 3 (DD3PCA3), a highly prostate cancer - specific gene. J Urology ,2003,62, ( Suppl 5A) :34 -43.
-
6Verhaegh GW, van Bokhoven A, Smit F, et al. Isolation and characterization of the promoter of the human prostate cancer - specific DD3 gene. J Biol Chem ,2000,275:37496 - 37503.
-
7Iwakiri J, Granbois K, Wehner N, et al. An analysis of urinary prostate specific antigen before and after radical prostatectomy:evidence for secretion of prostate specific antigen by the periurethral glands. J Urol, 1993,149, (4) :783 -786.
-
8Vicentini C, Luca GG, Angelucci A, et al. Detection of telomerase activity in prostate massage sample improves differentiating prostate cancer from benign prostatic hyperplasia. J Cancer Res Clin Oncol, 2004,130, ( 1 ) :217 -221.
-
9Rehman I, Azzouzi AR, Catto JWF, et al. Proteomic analysis of voided urine after prostatic massage from patients with prostate cancer:A pilot study. J Urol,2004,64 : 1238 - 1243.
-
10Hessels D, Klein Gunnewiek JMT, van Oort I, et al. DD3PCA3 - based molecular urine analysis for the diagnosis of prostate cancer. J Eur Urol 2003,44:8 - 16.
二级参考文献9
-
1Jemal A,Murray T,Ward E,et al.Cancer statistics,2005[J].CA Cancer J Clin,2005,55(1):10-30.
-
2Bussemakers MJ,van Bokhoven A,Verhaegh GW,et al.DD3:a new prostate-specific gene,highly overexpressed in prostate cancer[J].Cancer Res,1999,59(23):5975-5979.
-
3Walsh PC.Campbell's urology[M].8th ed.Philadelphia:Elsevier Science,2002.3065-3067.
-
4Gandini O,Luci L,Stigliano A,et al.Is DD3 a new prostate-specific gene[J]? Anticancer Res,2003,23(1A):305-308.
-
5de Kok JB,Verhaegh GW,Roelofs RW,et al.DD3PCA3,a very sensitive and specific marker to detect prostate tumors[J].Cancer Res,2002,62(9):2695-2698.
-
6van Gils MP,Stenman UH,Schalken JA,et al.Innovations in serum and urine markers in prostate cancer current european research in the P-Mark project[J].Eur Urol,2005,48(6):1031-1041.
-
7Iwakiri J,Granbois K,Wehner N,et al.An analysis of urinary prostate specific antigen before and after radical prostatectomy:evidence for secretion of prostate specific antigen by the periurethral glands[J].J Urol,1993,149(4):783-786.
-
8Vicentini C,Gravina GL,Angelucci A,et al.Detection of telomerase activity in prostate massage sample improves differentiating prostate cancer from benign prostatic hyperplasia[J].J Cancer Res Clin Oncol,2004,130(4):217-221.
-
9Fradet Y,Saad F,Aprikian A,et al.uPM3,a new molecular urine test for the detection of prostate cancer[J].Urology,2004,64(2):311-315.
共引文献3
-
1王毅(综述),贾本忠(审校).前列腺癌的实验室诊断进展[J].国际泌尿系统杂志,2008,28(6):763-767.
-
2陈启光,张哲,陈雪磊,杨琦,李振华,孔垂泽.前列腺癌中DD3的表达及意义[J].中国现代医学杂志,2011,21(4):400-403. 被引量:1
-
3韩涛,郭宏骞.长链非编码RNA与前列腺癌的研究进展[J].临床泌尿外科杂志,2013,28(6):473-476. 被引量:1
-
1刘鸿翔(综述),张海滨(审校).前列腺癌患者DD3mRNA表达及其意义的研究进展[J].国际泌尿系统杂志,2013,33(3):399-402.
-
2叶芳耘,张乐之,吴丽丽,刘连杰,郑成竹,薜一峰.K19mRNA与大肠癌淋巴结微转移关系的实验研究[J].世界华人消化杂志,1998,6(S2):329-330.
-
3王恩华,滕蕾,王培林.PTEN基因在原发性肝细胞癌中的表达[J].青岛大学医学院学报,2007,43(2):153-155. 被引量:7
-
4谢东华.NF-κB与泌尿系肿瘤[J].国际泌尿系统杂志,2001,22(S1):12-15.
-
5丁小文,郑树,丁小礼,韩明勇.乳腺癌患者外周血中组织特异性mRNA的表达及其临床意义[J].肿瘤防治杂志,2003,10(12):1254-1256. 被引量:2
-
6王科,张智宇,林春华,门昌平,于胜强,王健涛,张鹏,万逢春,柳东夫,高振利.前列腺癌患者外周血差异显示编码3基因mRNA的表达[J].中华实验外科杂志,2013,30(2):392-393. 被引量:2
-
7钟惟德.前列腺癌细胞凋亡相关的基因表达研究[J].现代临床医学生物工程学杂志,2000,6(3):232-233.
-
8蔡永洁,姜书传.DD3mRNA在前列腺癌早期诊断中的应用现状[J].辽宁医学院学报,2013,34(6):90-92. 被引量:1
-
9张新宇,史占军.一氧化氮与肿瘤侵袭和转移行为研究进展[J].国外医学(肿瘤学分册),1999,26(5):267-269. 被引量:7
-
10刘闽军.“饿死”前列腺癌[J].中国家庭医生,2015,0(16):56-57.