摘要
目的:观察醋酸奥曲肽治疗食管胃底静脉曲张破裂出血的疗效。方法:选择78例食管胃底静脉曲张破裂出血的患者,随机分为治疗组40例,对照组38例,其中治疗组40例除常规治疗外,加奥曲肽以50μg/h的速度持续静脉泵入,观察并记录两组止血起效时间、有效率及药物不良反应。对照组用垂体后叶素、硝酸甘油。结果:治疗组6、12、24、48、72h止血率分别为45%、77%、85%、92%、100%,对照组分别为13%、21%、55%、73%、84%。两组疗效比较,差异有统计学意义,P<0.01。结论:醋酸奥曲肽是治疗食管胃底静脉曲张破裂出血安全、有效的药物。
Objective：To observe the effects of octreotide acetate on patients with esophageal and gastric varices bleeding. Methods：Seventy eight patients with esophageal and gastric varices bleeding were divided into group randomly.40 patients were in the treatment group,38 patients were in the comparison group.The treatment group were given normol therapy and Octreotide 50 Ixg/h.Observed the time of available hemostatic,effective rate and side-effect,the comparison group were given Posterior Pituitary,Nitroglycerin. Results：The rate of available hemostatic in treatment group in 6,12,24,48,72 h were 45%,77%,85%,92%,100%,the comparison group were 13%,21%,55%,73%,84%.There were significnt differences between two groups,P〈0.01. Conclusion：Octreotide acetate is an efficacy and safety drug for the esophageal and gastric varices bleeding.
出处
《中国当代医药》
2009年第17期19-20,共2页
China Modern Medicine
