摘要
对感染鸡贫血病毒（ＣＡＶ）雏鸡新城疫（ＮＤ）疫苗免疫及其强毒攻击后局部免疫组织——盲肠扁桃体和哈德尔腺的ＩｇＡ、ＩｇＧ和ＩｇＭ抗体生成细胞数量的动态变化进行了检测。结果发现，ＣＡＶ感染雏鸡ＮＤ免疫后７、１４、２８ｄ及新城疫强毒（ｖＮＤＶ）攻击后，上述免疫组织的三种抗体生成细胞数量均不同程度地低于未感染ＣＡＶ的ＮＤ免疫对照雏鸡。其中盲肠扁桃体弥散区的ＩｇＡ减少最为明显。表明ＣＡＶ感染雏鸡消化道和呼吸道局部免疫组织对新城疫疫苗的体液免疫应答功能降低。新城疫强毒攻击后ＣＡＶ感染ＮＤ免疫雏鸡的免疫保护率也明显低于未感染ＣＡＶ的免疫对照雏鸡。
The experiment was undertaken to detect the dynamic changes of the number of the IgA,IgG,lgM antibody-producing cells in the local immune tissues,cecal tonsil and Harderian gland,post ND vaccination of chicks infected with chicken anemia virus(CAV)at one-day old.The experiment results were as follows:(1)The number of IgA,IgG,IgM antibody-producing cells in the mentional above immune tissues post ND vaccination of chicks infected with CAV,in different degrees respectively,were lower than those uninfected-vaccinated control chicks at 7～28 day post vaccination.The results of this study showed that humorresponse of local immune tissues of CAV-infected chicks to ND vaccine was significantluy decreased.(2) The immunoprotective efficacy of ND vaccinated chicks infected with CAV was markedly decreased in comparision with that of uninfected control chicks.
出处
《黑龙江畜牧兽医》
CAS
北大核心
1998年第6期1-3,共3页
Heilongjiang Animal Science And veterinary Medicine
基金
黑龙江省自然基金
东北农业大学资助
