摘要
目的:探讨血清超敏C反应蛋白(hs-CRP)与心血管危险因素的关系。方法:对388例健康成人(男223例,女165例,年龄47～53岁)的身高、体重、血压、心电图、血糖、血脂及血清hs-CRP等进行测定。结果:由低至高的血清hs-CRP四等分组(<2.1mg/L,2.1～5.0mg/L,5.1～8.0mg/L,>8.0mg/L)的心血管危险因素体重指数、血压、空腹血糖、高密度脂蛋白-胆固醇(HDL-C)组间差异非常显著(F=7.63～22.46,P均<0.001),总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白-胆固醇(LDL-C)的组间差异有显著性(F=2.89～8.88,P分别为0.031,0.022,0.015),四组心血管危险因素聚集检出率分别为32.3%,48.9%,58.0%,79.4%,差异有显著性(x2=28.12,P<0.001)。结论:血清hs-CRP与心血管危险因素(体重指数、血压、血糖和血脂)有关。
Objective： To study the associations of the serum high sensitive c-reactive protein （hs-CRP） with cardiovascular risk factors in Chinese normal adult population. Methods： Totally, 388 adults （223 men and 165 women） aged 47-53 persons were divided into four groups according hs--CRP level （〈2.1mg/L, 2.1-5.0 mg/L, 5.1-8.0 mg/L, 〉8.0 mg/L） and recorded in the study for clinic examinations involving anthropometry and measurements of blood pressure, fasting and 2 h plasma glucose and insulin levels, serum lipid profile and hs--CRP. Results： For the four groups according hs-- CRP level, there were significant difference of cardiovascular risk factors [BM1, blood pressure, fasting plasma glucose levels, HDL-C （F= 7. 62- 22. 46, P〈0.001 all） and TC, TG, LDL-C （F= 2.89-8.88, P〈0.05 all], and the rate of cluster of cardiovascular risk factors was 32.3%, 48.9%, 58.0%, 79. 4% （x^2 =28. 12, P〈0. 001） from the lowest to the highest quartile of hs--CRP level respectively. Conclusion： There may be a significant relationship among hs--CRP and cardiovascular risk factors in the Chinese normal middle aged population.
出处
《心血管康复医学杂志》
CAS
2009年第4期350-352,共3页
Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词
C反应蛋白质
心血管疾病
危险因素
心电描记术
C-reactive protein
Cardiovascular disease
Risk factors
Electrocardiography
