摘要
目的:检测不同基础心脏病所致慢性心力衰竭(CHF)患者的血浆apelin浓度。方法:按照纽约心脏病协会(NYHA)心功能分级标准和左室射血分数(LVEF<50%)选择68例心功能不全患者为心衰组,选择心功能正常者21例做对照组,应用酶联免疫吸附法(ELISA)检测血浆apelin水平,比较不同病因如高血压病、冠心病、扩张性心肌病所致心衰的血浆apelin浓度区别。结果:CHF组血浆apelin水平高于对照组[(5.07±0.75)ng/ml:(3.73±0.3)ng/ml,P<0.01];不同病因心衰血浆apelin含量无显著差别(P>0.05)。结论:CHF患者血浆apelin浓度高于心功能正常者,可考虑将apelin浓度检测作为心力衰竭患者筛查诊断指标之一。
Objective： To determine apelin levels in different categories heart patients with chronic congestive heart failure （CHF）. Methods： A total of 68 patients were selected according to NYHA cardiac function and left ventrieular ejection fraction （LVEF） 〈50 % examined by echocardiography （CHF group）, 21 patients without CHF were selected as the control group. The concentration of plasma apelin was measured by ELISA. Results： CHF patients had higher plasma apelin levels than patients without CHF [ （5.07±0.75） ng/ml ： （3.73±0.3） ng/ml, P〈0.01]. There were no significant difference among different categories cardiac desease patient with CHF （P〉0. 05）. Conclusion： Plasma apelin concentrations will be used to detect congestive heart failure
出处
《心血管康复医学杂志》
CAS
2009年第4期332-334,共3页
Chinese Journal of Cardiovascular Rehabilitation Medicine
