骨髓基质干细胞移植治疗心血管疾病的研究进展
摘要
心脏疾病如急性心肌梗死、各种心肌病等,由于心室重构,心肌细胞数量的减少,导致心功能下降,而心肌细胞移植作为一种全新的治疗方法应用于改善心功能及心肌活力,为此类心脏患者改善预后带来了希望。现就近年来国内外MSC自体移植在治疗心血管方面疾病的研究进展作一综述。
出处
《泸州医学院学报》
2009年第4期447-449,共3页
Journal of Luzhou Medical College
参考文献22
-
1Dezawa M ,lahashi I,Esaki M,et al,Sciatic nerve regeneration in ratsinduced by transplantation of in vitro diferentiated bone marrow stromcells [J].Eur J Neurosci,2001;14 (11):1771.
-
2PittengerMF,MackayAM,Beck SC,et al.Multilineage potential of adult haman mesenchymal stem cells[J].Science, 1999;284:143.
-
3Digirelamo CM,Stokes D,Colter D,et al.Propagation and senescence of human marrow stremal cells in culture:a simple colony-forming assay identifies samples with the greatest potential to propagate and diferentiate [J].Br J Haematol,1999;107:275.
-
4Reyes M,Vefinlm CM.Characterization of multipotent adultprogenitor cels,A subpopulation of mesenehymal stem cels[J].Ann N Y Acad Sci,2001;938:231.
-
5Grinnemo KH,Mansson A,Dellgren G,et al.Xenoreactivity andengraftment of human mesenchymal stem cells trans- planted intoinfarcted rat mycardium [J].Thorae Cardiovasc Surg,2004;127(5):1293.
-
6Tomita S,Mickle DA,Weisel RD,et al.Improved heart function with myogenesis and angiogenesis after autologous porcine bone real TOW stromal cell transplantation [J].J Thorac Cardiovasc Surg,2002;123(6):1132.
-
7Orlic D,Kajstur J,Chimenti S,et al.Mobilized bone marrowcellsrepair the infacted heart,improving function and survival[J].Proc Nat Acad Sci USA,2001;98(18):103.
-
8Tang J,Xie Q,Pan G,et al,Mesenchymal stem cells participateinangiogenesis and improve heart function in rat model of myocardial ishemia with reperfusion [J].Eur J Cardiothorac Surg,2006;30(2):353.
-
9Toma C,Pittenger MF,Cahill BS,et al,Human mesenchy real stem cells diferentiate to a cardiomyocyte phenotype in the adult murine heart[J].Circulation,2002,105(1):93.
-
10Ortiz LA,Gambeli F,McBride C,et al.Mesenchymal stem cell engraftment in lungs enhancedin responseto bleomycin exposurean d amelioratesitsfibmticefects [J].Prcc Natl Acad Sci USA,2003;100:8407.
二级参考文献25
-
1Niesler CU.Old dogmas and new hearts:a role for adult stem cells in cardiac repair[J]? Cardiovasc J S Afr,2004,15(4):184-189.
-
2Anderson DJ,Gage FH,Weissman IL.Can stem cells cross lineage boundaries[J]? Nat Med,2001,7(4):393-395.
-
3Murry CE,Soonpaa MH,Reinecke H,et al.Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts[J].Nature,2004,8;428 (6983):664-668.
-
4Alvarez DM,Pardal R,Garcia VJM,et al.Fusion of bonemarrow-derived cells with Purkinje neurons,cardiomyocytes and hepatocytes[J].Nature,2003,30;4 25 (6961):968-973.
-
5Alison MR,Poulsom R,Otto WR,et al.Recipes for adult stem cell plasticity:fusion cuisine or readymade[J]? J Clin Pathol,2004,57 (2):113-120.
-
6Harris RG,Herzog EL,Bruscia EM,et al.Lack of a fusion requirement for development of bone marrow-derived epithelia[J].Science,2004,2;305 (5680):90-93.
-
7Heissig B,Hattori K,Dias S,et al.Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand[J].Cell,2002,31;109(5):625-637.
-
8Yau TM,Tomita S,Weisel RD.Beneficial effect of autologous cell transplantation on infarcted heart function:comparison between bone marrow stromal cells and heart cells[J].Ann Thorac Surg,2003,75 (1):169-176.
-
9Wang JS,Shum TD,Galipeau J,et al.Marrow stromal cells for cellular cardiomyoplasty:feasibility and potential clinical advantages[J].J Thorac Cardiovasc Surg,2000,120 (5):999-1005.
-
10Muller-Ehmsen J,Kedes LH,Schwinger RH,et al.Cellular cardiomyoplasty a novel approach to treat heart disease[J].Congest Heart Fail,2002,8(4):220-227.
-
1葛均波.我国干细胞治疗心脏病临床研究现状与展望[J].中华心血管病杂志,2006,34(2):97-98. 被引量:13
-
2陈岭,徐宜,陆培红.改善心室重构的药物和方法[J].医学综述,2008,14(8):1255-1256. 被引量:1
-
3蒋雯,李庚山,林国生.干细胞与心肌细胞移植[J].实用临床医学(江西),2002(5):137-139.
-
4王脚苟,关瑞锦.骨髓基质干细胞与心脏疾病[J].心血管病学进展,2007,28(4):594-597. 被引量:1
-
5李立人,徐青.骨髓基质干细胞移植对糖尿病大鼠血糖的影响[J].苏州大学学报(医学版),2005,25(4):584-585. 被引量:3
-
6张昀.胡盛寿教授细谈干细胞VS心脏病[J].中国卫生人才,2002(4):28-29.
-
7史宇恒,魏宽海.坏死心肌修复的研究进展[J].国外医学(心血管疾病分册),1999,26(6):338-340.
-
8赵章勇(综述),杨鸿生(审校),张桂敏(审校),杨百晖(审校).外周血干细胞治疗缺血性心脏病的研究进展[J].中外医学研究,2010,8(7):17-18.
-
9吴旻,张元春,李玉光.心肌细胞移植对心功能影响实验研究的进展[J].汕头大学医学院学报,2001,14(1):61-62.
-
10吴学思.恢复心功能 不是不可能[J].大众医学,2006(6):15-15.