摘要
目的探讨血尿酸(SUA)、总胆红素(TBIL)水平与冠心病的关系。方法分析各组血SUA、TBIL、总胆固醇(TC)、低密度脂蛋白(LDL-C)等与冠心病的关系。结果冠心病组SUA水平为(359.70±79.83)μmol/L,较对照组(328.65±73.37)μmol/L增高,TBIL水平为(10.95±3.72)μmol/L,较对照组(14.02±5.38)μmol/L降低,差异均有统计学意义(P<0.05),且随着冠状动脉病变支数增多,TBIL数值减小,并且3个亚组之间TBIL水平差异有统计学意义(P<0.05)。结论SUA水平升高、TBIL水平降低是冠心病的重要危险因素,且TBIL水平可能与冠心病受累血管支数有关,提示TBIL与冠心病血管病变的范围有关。
Objective To study the relationship between the level of serum uric acid（SUA）,total bilirubin（TBIL） and coronary heart disease（CHD）. Methods The clinical data of 339 inpatients undergoing coronary angiography in our department from April 2006 to April 2008 were retrospectively analyzed. According to the results of coronary angiography,those patients with stenosis of inner diameter of coronary artery larger than 50% were CHD group. CHD patients were furtherly divided into subgroups with narrowness at single,double and multiple branches according to the number of coronary artery involved. Those with stenosis of inner diameter of coronary artery less than 50 % were control group. The relationship between SUA,TBIL,TC, LDL-C and CHD in each group was analyzed. Results The level of SUA in CHD group was（359.70±79.83）μmol/L,which was higher than that in control group（328.65±73.37）μmol/L. The level of TBIL in CHD group was （10.95±3.72）μmol/L,which was lower than that in control group（14.02 ± 5.38）μmol/L. The differences were significant. With the number of stenosed branches increasing, the level of TBIL was significantly decreased,and there was significant difference among the three subgroups in the level of TBIL. Concision The increase of SUA and the decrease of TBIL are important risk factors of CHD,and the level of TBIL may be associated with the number of coronary arteries involved. It suggests that TBIL may play a very important role in the development of CHD.
出处
《重庆医学》
CAS
CSCD
北大核心
2009年第17期2199-2200,2202,共3页
Chongqing medicine
关键词
冠心病
血尿酸
总胆红素
coronary heart disease
serum uric acid
total hilirubin
