摘要
目的探讨毛细支气管炎患儿血胸腺和活化调节趋化因子(TARC)的临床意义。方法采用ELISA方法测定毛细支气管炎急性期、恢复期和非喘息性肺炎患儿外周血中TARC的浓度。结果毛细支气管炎患儿急性期血TARC的水平显著高于非喘息性肺炎患儿(P<0.01)。毛细支气管炎恢复期患儿血清TARC水平较急性期明显降低(P<0.01),但仍高于非喘息性肺炎患儿的水平,有显著性差异(P<0.05)。结论TARC在毛细支气管炎的发病机制中有不可忽视的作用,TARC拮抗剂在毛细支气管炎治疗上可能有一定的作用。
Objective To explore the clinical significance of peripheral blood thymus-and activation-regulated chemokine（TARC）determination in infants with bronchiolitis.Methods The level of TARC was determined in the infants with bronchiolitis in the acute and recovery stages,and the infants with no-wheezing pneumonia by ELISA.Results TARC levels in the infants with bronchiolitis in acute stage were higher than those in no-wheezing pneumonia group（P〈0.01）.The TARC levels in the infants with bronchiolitis in the convalescent stage were lower than those in acute stage（P〈0.01）,but higher than those in no-wheezing pneumonia group（P〈0.05）.Conclusion The TARC is elevated in bronchiolitis,and TARC may participate in the pathogenesis of bronchiolitis.TARC receptor antagonist may play an important role in the treatment of bronchiolitis.
出处
《华中医学杂志》
2009年第4期199-201,共3页
Central China Medical Journal
